CAJ | 학술논문

目的?研究因颅脑外伤后引起的迟发性顽固性癫痫的发病基础及最佳手术方式.方法?选取我院收治的因颅脑外伤引起的迟发性癫痫的患者50例,作为研究对象随机分成A组和B组,各25例,分别采用不同的手术方式,A组采用常规的病理灶切除术,B组在A组的基础上配合标准前颞叶切除术,手术后随访6~12个月,根据疗效评价标准比较两组患者术后的疗效.根据引起颅脑外伤的病因及术后病理分析颅脑外伤引起的迟发性癫痫病变组织的病理特点,研究其发病基础.结果?根据引起颅脑外伤的病因和术后病理分析,其发病基础主要为外伤造成的脑叶软化灶形成和瘢痕增生;手术后随访6~12个月,其中A组总有效率为60%,B组总有效率占92%,P均<0.05,具有统计学意义.结论?颅脑外伤后迟发性顽固性癫痫的主要发病基础是外伤造成的脑软化灶和瘢痕增生.B组的手术方式能够有效提高治疗的效果,是颅脑外伤后迟发性顽固性癫痫患者选择的最佳手术方式,手术随访疗效显著.
목적?연구인로뇌외상후인기적지발성완고성전간적발병기출급최가수술방식.방법?선취아원수치적인로뇌외상인기적지발성전간적환자50례,작위연구대상수궤분성A조화B조,각25례,분별채용불동적수술방식,A조채용상규적병리조절제술,B조재A조적기출상배합표준전섭협절제술,수술후수방6~12개월,근거료효평개표준비교량조환자술후적료효.근거인기로뇌외상적병인급술후병리분석로뇌외상인기적지발성전간병변조직적병리특점,연구기발병기출.결과?근거인기로뇌외상적병인화술후병리분석,기발병기출주요위외상조성적뇌협연화조형성화반흔증생;수술후수방6~12개월,기중A조총유효솔위60%,B조총유효솔점92%,P균<0.05,구유통계학의의.결론?로뇌외상후지발성완고성전간적주요발병기출시외상조성적뇌연화조화반흔증생.B조적수술방식능구유효제고치료적효과,시로뇌외상후지발성완고성전간환자선택적최가수술방식,수술수방료효현저.
Objective?To?study?for?craniocerebral?trauma?caused?by?delay?sex?with?intractable?epilepsy?pathogenesis?of?foundation?and?the?best?operation?method.?Methods?The?patients?of?craniocerebral?trauma?for?our?cause?delay?epilepsy?patients?50?cases,?as?the?research?object?random?divided?into?group?A?and?group?B,?each?25?cases,?we?adopt?different?operation?method,?A?group?of?using?conventional?pathology?stove?resection,?group?B?in?group?A?with?standard?on?the?basis?of?former?temporal?lobectomy,?surgery?were?followed?up?for?6?~?12?months,?according?to?curative?effect?evaluation?standard?compared?between?the?two?groups?patients?postoperative?effect.?According?to?the?etiology?of?craniocerebral?trauma?caused?and?postoperative?pathologic?analysis?craniocerebral?trauma?caused?by?the?late-occurred?epilepsy?variable?tissue?pathological?characteristics,?study?the?onset?of?foundation.?Results?According?to?cause?craniocerebral?trauma?and?the?causes?of?postoperative?pathological?analysis,?the?onset?of?foundation?is?mainly?caused?by?trauma?of?lobes?softening?stove?formation?and?scar?hyperplasia;?After?surgery?were?followed?up?for?6?~?12?months,?the?total?effective?rate?was?60%?in?group?A,?B?group?total?effectiveness?92%,?P<0.05, with statistical significance. Conclusion?Craniocerebral?trauma?with?intractable?epilepsy?late-occurred?the?main?disease?caused?by?trauma?is?based?on?the?encephalomalacia?stove?and?scar?hyperplasia.?B?group?of?operation?method?can?effectively?enhance?the?treatment?effect,?is?after?craniocerebral?trauma?with?intractable?epilepsy?late-occurred?patients?to?choose?the?best?operation?method,?surgery?follow-up?curative?effect?is?distinct.