CAJ | 학술논문

目的探索3种不同制剂的奥美拉唑治疗胃十二指肠溃疡的疗效研究.方法将120例符合胃十二指肠溃疡诊断的患者随机分为3组, A组用奥美拉唑肠溶胶囊口服,20mg/次,日一次.B组用奥美拉唑肠溶片口服,20mg/次,日一次.C组用注射用奥美拉唑钠80mg加入,0.9%氯化钠溶液100mL中静脉滴注,日一次.三组治疗时间均为4周.结果三种不同制剂的奥美拉唑在治疗胃十二指肠溃疡的胃镜疗效和临床疗效上没有显著性差异.而且三种不同制剂的奥美拉唑在治疗过程中均未出现严重不良反应.结论说明三种不同制剂的奥美拉唑在临床使用上没有差异,可以互相代替使用.
목적탐색3충불동제제적오미랍서치료위십이지장궤양적료효연구.방법장120례부합위십이지장궤양진단적환자수궤분위3조, A조용오미랍서장용효낭구복,20mg/차,일일차.B조용오미랍서장용편구복,20mg/차,일일차.C조용주사용오미랍서납80mg가입,0.9%록화납용액100mL중정맥적주,일일차.삼조치료시간균위4주.결과삼충불동제제적오미랍서재치료위십이지장궤양적위경료효화림상료효상몰유현저성차이.이차삼충불동제제적오미랍서재치료과정중균미출현엄중불량반응.결논설명삼충불동제제적오미랍서재림상사용상몰유차이,가이호상대체사용.
Objective To explore three different formulations of omeprazole in the treatment of gastric ulcer efficacy. Methods Firstly, we choose 120 Gastroduodenal Ulcers patients who conform to the research diagnosis standard.Then the patients were divided into three groups. Group A were cured by the omeprazole enteric-coated capsules, 20mg/day time.B group were cured by the omeprazole enteric-coated tablets, 20mg/day time. Group C were cured by the Omeprazole Sodium injection 80mg what intravenous infusion, once a day. Three groups of treatment time was 4 weeks. Results No significant difference between the three different formulations of omeprazole in the treatment of gastroduodenal ulcers the gastroscope efficacy and clinical efficacy. And three different formulations of omeprazole were no serious adverse reactions during treatment.Conclusion lllustrating three different formulations of omeprazole were no difference in the clinical use, instead of using other.