CAJ | 학술논문

目的探讨肝硬化患者幽门螺杆菌感染和上消化道出血的关系.方法选取2010年11月至2011年11月本院收治的肝硬化患者87例,对本组患者的幽门杆菌感染、食管胃底静脉曲张、消化性溃疡情况进行分析.结果本组合并上消化道出血26例,其中消化道溃疡出血18例,食管胃底静脉曲张破裂出血5例,消化(道)性溃疡合并出血2例,门脉高压性胃病出血1例;本组幽门螺杆菌感染阳性51例,合并上消化道出血19例;幽门螺杆菌染阴性36例,合并上消化道出血7例.幽门螺杆菌感染阳性合并上消化道出血发生率明显高于幽门螺杆菌感染阴性患者,有统计学意义.结论幽门螺杆菌感染和肝源性消化性溃疡有一定关系,存在幽门螺杆菌的肝硬化患者发生上消化道出血的概率显著上升,根除治疗肝硬化患者幽门螺杆菌感染对降低上消化道出血具有重要意义.
목적탐토간경화환자유문라간균감염화상소화도출혈적관계.방법선취2010년11월지2011년11월본원수치적간경화환자87례,대본조환자적유문간균감염、식관위저정맥곡장、소화성궤양정황진행분석.결과본조합병상소화도출혈26례,기중소화도궤양출혈18례,식관위저정맥곡장파렬출혈5례,소화(도)성궤양합병출혈2례,문맥고압성위병출혈1례;본조유문라간균감염양성51례,합병상소화도출혈19례;유문라간균염음성36례,합병상소화도출혈7례.유문라간균감염양성합병상소화도출혈발생솔명현고우유문라간균감염음성환자,유통계학의의.결론유문라간균감염화간원성소화성궤양유일정관계,존재유문라간균적간경화환자발생상소화도출혈적개솔현저상승,근제치료간경화환자유문라간균감염대강저상소화도출혈구유중요의의.
Objective To investigate the liver cirrhosis patients with Helicobacter pylori infection and hemorrhage of upper digestive tract relationship. Methods From 2010 November to 2011 November were treated in our hospital 87 cases of cirrhosis, for this group of patients with Helicobacter pylori infection, esophageal varices of fundus of stomach, peptic ulcer were analyzed. Results The combined with upper gastrointestinal hemorrhage in 26 cases, including 18 cases of peptic ulcer, esophageal and gastric varices bleeding in 5 cases (tract), digestive ulcer with bleeding in 2 cases, bleeding portal hypertensive gastropathy in 1 cases;this group of Helicobacter pylori infection was positive in 51 cases, combined with upper digestive gastrointestinal hemorrhage in 19 cases;Helicobacter pylori infection negative in 36 cases, combined with upper gastrointestinal hemorrhage in 7 cases. Helicobacter pylori infection complicated with hemorrhage of upper digestive tract had a significantly higher incidence of Helicobacter pylori infection in patients with negative, with statistical significance. Conclusion Helicobacter pylori infection and hepatogenic peptic ulcer have a certain relationship, the presence of Helicobacter pylori in patients with liver cirrhosis upper gastrointestinal bleeding occurred rate increased significantly, eradication therapy in patients with liver cirrhosis and Helicobacter pylori infection on reduction of hemorrhage of upper digestive tract has important significance.