中国肿瘤临床
中國腫瘤臨床
중국종류림상
CHINESE JOURNAL OF CLINICAL ONCOLOGY
2012年
22期
1810-1813
,共4页
刘学奎%刘志民%刘巍巍%李秋梨%李浩%欧阳电%李铨%张欣睿%郭朱明%曾宗渊
劉學奎%劉誌民%劉巍巍%李鞦梨%李浩%歐暘電%李銓%張訢睿%郭硃明%曾宗淵
류학규%류지민%류외외%리추리%리호%구양전%리전%장흔예%곽주명%증종연
激光手术%喉肿瘤%复发率%前联合
激光手術%喉腫瘤%複髮率%前聯閤
격광수술%후종류%복발솔%전연합
Laser therapy%Laryngeal neoplasm%Recurrence%Anterior commissure
目的:分析CO2激光手术治疗声门型喉癌局部复发与前联合受侵犯的关系.方法:回顾性分析2008年1月至2010年12月中山大学肿瘤防治中心中133例激光手术治疗的早期声门型喉癌患者资料.其中包括侵犯前联合患者48例和前联合未受侵85例.133例中原位癌(Tis)40例,T1a 58例,T1b 19例,T25例,T31例.术后随诊6~42个月.比较前联合受累组与前联合未受累组的局部复发率.结果:133例支撑喉镜下CO2激光手术后21例局部复发,局部复发率为15.79%(21/133).其中Tis复发率为17.50%(7/40)、T1a为8.62%(5/58)、T1b为36.84%(7/19)、T2为13.33%(2/15),T31例无复发,各组间复发率无显著性差异(P>0.05).病变侵犯前联合复发率为25.00%(12/48),病变未侵犯前联合复发率为10.59%(9/85),两组间有显著性差异(P<0.05).133例激光手术治疗患者中死亡4例.结论:激光手术治疗侵犯前联合的早期声门型喉癌复发率高,其治疗价值值得进一步研究.
目的:分析CO2激光手術治療聲門型喉癌跼部複髮與前聯閤受侵犯的關繫.方法:迴顧性分析2008年1月至2010年12月中山大學腫瘤防治中心中133例激光手術治療的早期聲門型喉癌患者資料.其中包括侵犯前聯閤患者48例和前聯閤未受侵85例.133例中原位癌(Tis)40例,T1a 58例,T1b 19例,T25例,T31例.術後隨診6~42箇月.比較前聯閤受纍組與前聯閤未受纍組的跼部複髮率.結果:133例支撐喉鏡下CO2激光手術後21例跼部複髮,跼部複髮率為15.79%(21/133).其中Tis複髮率為17.50%(7/40)、T1a為8.62%(5/58)、T1b為36.84%(7/19)、T2為13.33%(2/15),T31例無複髮,各組間複髮率無顯著性差異(P>0.05).病變侵犯前聯閤複髮率為25.00%(12/48),病變未侵犯前聯閤複髮率為10.59%(9/85),兩組間有顯著性差異(P<0.05).133例激光手術治療患者中死亡4例.結論:激光手術治療侵犯前聯閤的早期聲門型喉癌複髮率高,其治療價值值得進一步研究.
목적:분석CO2격광수술치료성문형후암국부복발여전연합수침범적관계.방법:회고성분석2008년1월지2010년12월중산대학종류방치중심중133례격광수술치료적조기성문형후암환자자료.기중포괄침범전연합환자48례화전연합미수침85례.133례중원위암(Tis)40례,T1a 58례,T1b 19례,T25례,T31례.술후수진6~42개월.비교전연합수루조여전연합미수루조적국부복발솔.결과:133례지탱후경하CO2격광수술후21례국부복발,국부복발솔위15.79%(21/133).기중Tis복발솔위17.50%(7/40)、T1a위8.62%(5/58)、T1b위36.84%(7/19)、T2위13.33%(2/15),T31례무복발,각조간복발솔무현저성차이(P>0.05).병변침범전연합복발솔위25.00%(12/48),병변미침범전연합복발솔위10.59%(9/85),량조간유현저성차이(P<0.05).133례격광수술치료환자중사망4례.결론:격광수술치료침범전연합적조기성문형후암복발솔고,기치료개치치득진일보연구.
Objective: This work aims to analyze the relationship between local recurrence and location of the tumor in early glot-tic carcinoma after CO2 laser endoscopic resection. Methods: Data of 133 early glottic carcinoma cases, which were treated with laser surgery and were hospitalized at the cancer center of Sun Yan-Sen University from 2008 to 2010, were reviewed retrospectively. Of the 133 cases, 48 involved the anterior commissure and the other 85 did not. Of the total cases, Tis stage lesion (tumor in situ) was found in 58 cases, T1a stage in 58, T1b stage in 19, T2 stage in 15, and T3 stage in only 1. The follow-up period ranged from 6 to 42 months. The lo-cal recurrence rate between the involvement and non-involvement of anterior commissure was compared. Results: Local recurrence was detected in 21 of the 133 cases with early glottic laryngeal carcinoma after CO2 laser surgery. The local recurrence rate was 15.79%(21/133). The recurrence rates of T1a, T1b, T2, and T3 were 8.62%, 36.84%, 13.33%, and 0%, respectively. No significant difference was found among the four groups (P≥0.05). Among the 135 patients presenting with early glottic cancer, the anterior commissure was in-volved in 48 cases, with a local recurrence rate of 25% (12/48). In 85 of the cases without anterior commissure involvement, the local recurrence rate was 10.59% (9/85). Significant differences were found between the two groups (P≤0.05). Of the 133 patients who re-ceived CO2 laser surgery as the only therapy, 129 survived and 4 died. Conclusion: After laser microsurgery of early glottic carcinoma, a higher rate of tumor recurrence was found in the lesions with anterior commissure involvement. This finding needs further research.
