CAJ | 학술논문

目的:探讨早期胃癌淋巴结转移的危险因素.方法:回顾性分析2005年1月至2010年12月安徽医科大学附属省立医院普外科收治的215例早期胃癌患者的临床病理资料,并研究早期胃癌淋巴结转移与临床病理因素的关系.结果:215例患者中淋巴结转移者36例,单因素分析显示:肿瘤最大直径(P=0.022)、浸润深度(P=0.003)、Hp感染情况(P=0.004)均与早期胃癌淋巴结转移有关.Logistic多因素回归分析显示:肿瘤的浸润深度与早期胃癌淋巴结转移有关(P=0.002).结论:肿瘤的浸润深度是影响早期胃癌淋巴结转移的独立危险因素.
목적:탐토조기위암림파결전이적위험인소.방법:회고성분석2005년1월지2010년12월안휘의과대학부속성립의원보외과수치적215례조기위암환자적림상병리자료,병연구조기위암림파결전이여림상병리인소적관계.결과:215례환자중림파결전이자36례,단인소분석현시:종류최대직경(P=0.022)、침윤심도(P=0.003)、Hp감염정황(P=0.004)균여조기위암림파결전이유관.Logistic다인소회귀분석현시:종류적침윤심도여조기위암림파결전이유관(P=0.002).결론:종류적침윤심도시영향조기위암림파결전이적독립위험인소.
Objective: This study was designed to investigate the risk factors for lymph node metastasis in early gastric cancer. Methods: We retrospectively analyzed the clinicopathological data of 215 patients with early gastric cancer treated at the Anhui Province Hospital from January 2005 to December 2010. The relationship between lymph node metastasis and cliniopathological factors was evaluated by univariate and multivariable logistic regression analyses. Results: Univariate analysis showed that tumor size (P=0.001), depth of invasion (P=0.000), and Helicobacter pylori infection (P=0.000) were associated with lymph node metastasis. Multivariable logistic regression analysis revealed that the depth of invasion was considered a significant risk factor (P<0.05). Conclusion: The depth of invasion is the risk factor for lymph node metastasis in early gastric cancer.