CAJ | 학술논문

目的:探讨影响结直肠癌腹膜种植转移的临床病理相关因素.方法:收集2005年1月至2009年12月广西医科大学第一附属医院的结直肠癌患者1170例的临床病理资料,研究结直肠癌腹膜种植转移与临床病理因素的关系.采用非条件Logistic回归单因素分析,并对有统计学意义的变量进行非条件Logistic回归多因素分析.结果:1170例结直肠癌患者中,腹膜种植转移92例(7.86%).单因素分析显示,患者的年龄、肿瘤部位、浸润肠腔周径、肿瘤最大径、组织病理学类型、分化程度、肠壁浸润深度、淋巴结转移和血CEA水平与结直肠癌腹膜转移有关.Logistic多因素分析显示,肿瘤部位、浸润肠腔周径、分化程度、肠壁浸润深度、淋巴结转移和血CEA水平与结直肠癌腹膜转移的有关.结论:肿瘤部位、浸润肠腔周径、分化程度、肠壁浸润深度、淋巴结转移和血CEA水平是结直肠癌发生腹膜转移的独立相关因素.
목적:탐토영향결직장암복막충식전이적림상병리상관인소.방법:수집2005년1월지2009년12월엄서의과대학제일부속의원적결직장암환자1170례적림상병리자료,연구결직장암복막충식전이여림상병리인소적관계.채용비조건Logistic회귀단인소분석,병대유통계학의의적변량진행비조건Logistic회귀다인소분석.결과:1170례결직장암환자중,복막충식전이92례(7.86%).단인소분석현시,환자적년령、종류부위、침윤장강주경、종류최대경、조직병이학류형、분화정도、장벽침윤심도、림파결전이화혈CEA수평여결직장암복막전이유관.Logistic다인소분석현시,종류부위、침윤장강주경、분화정도、장벽침윤심도、림파결전이화혈CEA수평여결직장암복막전이적유관.결론:종류부위、침윤장강주경、분화정도、장벽침윤심도、림파결전이화혈CEA수평시결직장암발생복막전이적독립상관인소.
Objective: This study aims to investigate the clinicopathologic factors related to peritoneal metastasis in 1170 colorectal cancer patients. Methods: Clinicopathologic data from 1170 colorectal cancer patients treated in The First Affiliated Hospital, Guangxi Medical University between January 2005 and December 2009 were collected. The associations between peritoneal metastasis and clini-copathological factors were evaluated by univariate and multivariate logistic regression analyses. All analyses were conducted using SPSS software (version 13.0). Results: Of the 1170 cases, 92 (7.86%) had peritoneal metastases. Univariate analysis showed that age, tumor location, tumor size (cm), tumor circumference, histological type, tumor differentiation, invasion depth, lymph node metastasis, and serum carcinoembryonic antigen (CEA) levels were predictors that could affect peritoneal metastasis. Multivariate analysis showed that tumor location, tumor circumference, tumor differentiation, invasion depth, lymph node metastasis, and serum CEA levels were independent factors related to peritoneal metastasis from colorectal cancer. Conclusion: Tumor location, tumor circumference, tumor differentiation, invasion depth, lymph node metastasis, and serum CEA levels were clinicopathologic factors related to peritoneal metastasis from colorectal carcinoma.