CAJ | 학술논문

目的探讨应用不同组织多普勒技术评估高血压病不同左心室几何构型阶段主动脉壁平滑肌运动的价值.方法测定高血压病患者主动脉壁的组织速度显像、组织追踪显像、应变显像和应变率显像曲线,并且分别测量每一曲线上的收缩期峰值速度(AOPVs)、舒张早期运动速度(AOVe)、舒张晚期运动速度(AOVa)、收缩期峰值位移(AOPDs)、收缩期峰值应变(AOPSs)、收缩期峰值应变率(AOPSRs)、舒张早期应变率(AOEsr)、舒张晚期应变率(AOAsr);并计算AOVe/AOVa,AOEsr/AOAsr.结果对照组与正常构型组、向心性重构组、向心性肥厚组、离心性肥厚组的AOPSs、AOVe、AOVa、AOEsr、AOEsr/Asr测值,向心性重构组、向心性肥厚组、离心性肥厚组的AOPDs测值,正常构型组、向心性重构组、向心性肥厚组的AOVe/Va测值差异均有统计学意义(均P<0.05);正常构型组与对照组、向心性重构组、向心性肥厚组、离心性肥厚组的AOPVs、AOPDs测值差异均有统计学意义(均P<0.05);向心性重构组与对照组、向心性肥厚组、离心性肥厚组的AOPVs测值,正常构型组、向心性肥厚组、离心性肥厚组的 AOPSs测值差异均有统计学意义(均P<0.05);离心性肥厚组与对照组、正常构型组、向心性重构组、向心性肥厚组的AOAsr、AOVe/Va测值差异均有统计学意义(均P<0.05);正常构型组、离心性肥厚组与对照组、向心性重构组、向心性肥厚组的AOPSRs测值、正常构型组、向心性重构组与向心性肥厚组、离心性肥厚组的AOEsr/Asr测值差异具有统计学意义(均P<0.05).结论(1)组织多普勒技术可评价高血压病不同左心室几何构型阶段的主动脉壁平滑肌的运动;(2)利用组织多普勒参数可定量评估高血压病在不同左心室几何构型阶段主动脉壁平滑肌的功能.
목적탐토응용불동조직다보륵기술평고고혈압병불동좌심실궤하구형계단주동맥벽평활기운동적개치.방법측정고혈압병환자주동맥벽적조직속도현상、조직추종현상、응변현상화응변솔현상곡선,병차분별측량매일곡선상적수축기봉치속도(AOPVs)、서장조기운동속도(AOVe)、서장만기운동속도(AOVa)、수축기봉치위이(AOPDs)、수축기봉치응변(AOPSs)、수축기봉치응변솔(AOPSRs)、서장조기응변솔(AOEsr)、서장만기응변솔(AOAsr);병계산AOVe/AOVa,AOEsr/AOAsr.결과대조조여정상구형조、향심성중구조、향심성비후조、리심성비후조적AOPSs、AOVe、AOVa、AOEsr、AOEsr/Asr측치,향심성중구조、향심성비후조、리심성비후조적AOPDs측치,정상구형조、향심성중구조、향심성비후조적AOVe/Va측치차이균유통계학의의(균P<0.05);정상구형조여대조조、향심성중구조、향심성비후조、리심성비후조적AOPVs、AOPDs측치차이균유통계학의의(균P<0.05);향심성중구조여대조조、향심성비후조、리심성비후조적AOPVs측치,정상구형조、향심성비후조、리심성비후조적 AOPSs측치차이균유통계학의의(균P<0.05);리심성비후조여대조조、정상구형조、향심성중구조、향심성비후조적AOAsr、AOVe/Va측치차이균유통계학의의(균P<0.05);정상구형조、리심성비후조여대조조、향심성중구조、향심성비후조적AOPSRs측치、정상구형조、향심성중구조여향심성비후조、리심성비후조적AOEsr/Asr측치차이구유통계학의의(균P<0.05).결론(1)조직다보륵기술가평개고혈압병불동좌심실궤하구형계단적주동맥벽평활기적운동;(2)이용조직다보륵삼수가정량평고고혈압병재불동좌심실궤하구형계단주동맥벽평활기적공능.
Objective To evaluate the application of tissue Doppler imaging in measurement of aortic wal motion in dif-ferent geometric configuration stage of left ventricle in patients with essential hypertension (EH). Methods The curves of tissue velocity imaging, tissue tracking imaging, strain imaging and strain rate imaging of aortic wal were obtained, and the peak sys-tolic velocity of aorta (AOPVs), peak systolic displacement of aorta (AOPDs), peak systolic strain of aorta (AOPSs), peak systolic strain rate of aorta (AOPSRs) , early diastolic velocity of aorta (AOVe), atrial systolic velocity of aorta (AOVa), early diastolic strain rate of aorta (AOEsr) and atrial systolic strain rate of aorta (AOAsr) were measured in each curves. The AOVe/AOVa and AOEsr/AOAsr were calculated. Results There were statistical differences in the mean AOPSs, AOVe, AOVa, AOEsr and AOEsr/Asr between control group (CG) and the left ventricular normal geometry group (LV-NGG), left ventricular concentric re-modeling group (LV-CRG), left ventricular concentric hypertrophy group (LV-CHG) , left ventricular eccentric hypertrophy group (LV-EHG); in the mean AOPDs between the CG and the LV-CRG, LV-CHG, LV-EHG; in the mean AOVe/Va between the CG and the LV-NGG , LV-CRG, LV-CHG f (P<0.05). There were statistical differences in the mean AOPVs and AOPDs between the LV-NGG and CG, LV-CRG, LV-CHG, LV-EHG (P<0.05). There were statistical differences in the mean AOPVs between the LV-CRG and CG, LV-CHG, LV-EHG;in the mean AOPSs between the LV-CRG and LV-NGG, LV-CHG, LV-EHG (P<0.05). There were statistical differences in the mean AOPVs between the LV-CRG and the CG, LV-CHG, LV-EHG(P<0.05). There were statistical differences in the mean AOAsr and AOVe/Va between the LV-EHG and the CG, LV-NGG, LV-CRG LV-CHG(P<0.05). There were statistical differences in the mean AOPSRs between the LV-NGG, LV-EHG and the CG, LV-CRG, LV-CHG;in the mean AOEsr/Asr between the LV-NGG, LV-CRG and the LV-EHG, LV-CHG (P<0.05). Conclusion The motions and the smooth muscle function of aortic wal s in different geometric configuration stage of left ventricle in patients with EH can be esti-mated by tissue Doppler techniques.