CAJ | 학술논문

目的:探讨宫颈液基细胞学与活检组织病理学在宫颈病变筛查中的价值.方法:对18356例经宫颈液基细胞学检查发现异常者在阴道镜下活检的患者临床及病理资料进行回顾性分析.结果:LCT 显示:18356例中,ASCUS 以上的有1256例,阳性率为6.8%,其中 ASCUS 占51.8%,LSIL占29.5%,HSIL 占10.6%.宫颈活检:慢性炎症占39.7%,CIN Ⅰ占37.3%,CIN Ⅱ占13.6%,CIN Ⅲ占8.9%,宫颈癌占0.4%.结论:LCT 液基细胞学检测系统是一种有效的宫颈癌前病变筛查方法.对 LCT 阳性病例行阴道镜下活检,能大大提高宫颈癌前病变及宫颈癌早期检出率,减少漏诊的发生.
목적:탐토궁경액기세포학여활검조직병이학재궁경병변사사중적개치.방법:대18356례경궁경액기세포학검사발현이상자재음도경하활검적환자림상급병리자료진행회고성분석.결과:LCT 현시:18356례중,ASCUS 이상적유1256례,양성솔위6.8%,기중 ASCUS 점51.8%,LSIL점29.5%,HSIL 점10.6%.궁경활검:만성염증점39.7%,CIN Ⅰ점37.3%,CIN Ⅱ점13.6%,CIN Ⅲ점8.9%,궁경암점0.4%.결론:LCT 액기세포학검측계통시일충유효적궁경암전병변사사방법.대 LCT 양성병례행음도경하활검,능대대제고궁경암전병변급궁경암조기검출솔,감소루진적발생.
Objective:To evaluate the value of liquid-based cytology (LCT) and histopathology of colposcopic biopsy in cervical screening.Methods:The cervical LCT results of 18 356 cases were analyzed,follow up diagnoses of colposcopic biopsy were available for those cytological abnormalities,then we performed a retrospective analysis of those clinical and pathological data.Results:Among 18 356 patients receiving LCT,1256 patients were diagnosed as Above-ASCUS pathological changes,the positive detection rate was 6.8%.Among these,ASCUS,LSIL and HSIL were 51.8%,29.5% and 10.6%,respectively. Among 1256 patients receiving colposcopic biopsy,39.7% were diagnosed as chronic inflammation,and cervical intraepithelial neoplasiaⅠ(CINⅠ) were 37.3%, CIN Ⅱ were 13.6%,CIN Ⅲ were 8.9% and cervical cancer were 0.4%.Conclusion:LCT liquid-based cytology technology is an effective method in screening of cervical precancerous disease.Combining with colposcopic biopsy among patients with abnormal LCT results,can not only improve the detection rate of cervical precancerous lesions and early stage of cervical cancer,but also reduce the incidence of missed diagnosis,significantly.