CAJ | 학술논문

目的:探讨乌灵胶囊联合苯磺酸氨氯地平治疗对高血压病伴焦虑症患者的临床效果.方法:将90例高血压病伴有焦虑症状的患者,随机分为三组各30例,A 组予以氨氯地平5mg,1次/d 降压治疗;B 组加用帕罗西汀20mg,1次/d;C 组加用乌灵胶囊3粒,3次/d.4周后观察各组降压有效率及药物不良反应.结果:降压有效率 A 组为53.3%,B 组为83.3%,C 组为80.0%,B、C 两组与 A 组比较,差异有统计学意义(P<0.05);C 组低于 B 组,但差异无统计学意义(P>0.05);B 组出现恶心、食欲减退、口干、失眠等,C 组无不良反应.结论:对高血压病伴焦虑症状的患者,氨氯地平联合应用帕罗西汀或乌灵胶囊能明显提高疗效,乌灵胶囊副作用少,易于患者耐受.
목적:탐토오령효낭연합분광산안록지평치료대고혈압병반초필증환자적림상효과.방법:장90례고혈압병반유초필증상적환자,수궤분위삼조각30례,A 조여이안록지평5mg,1차/d 강압치료;B 조가용파라서정20mg,1차/d;C 조가용오령효낭3립,3차/d.4주후관찰각조강압유효솔급약물불량반응.결과:강압유효솔 A 조위53.3%,B 조위83.3%,C 조위80.0%,B、C 량조여 A 조비교,차이유통계학의의(P<0.05);C 조저우 B 조,단차이무통계학의의(P>0.05);B 조출현악심、식욕감퇴、구간、실면등,C 조무불량반응.결론:대고혈압병반초필증상적환자,안록지평연합응용파라서정혹오령효낭능명현제고료효,오령효낭부작용소,역우환자내수.
Objective: To investigate clinical effects of Wuling capsule combined with amlodipine besylate. Methods: To divide 90 patients into three groups (30 for each), A group took amlodipine besylate 5mg/d; B group took paroxetine 20mg/d more; C group took 3 Wuling capsules/d more; and side effects and efficacy of relieving HBP were compared after 4 weeks. Result: The efficacy of relieving HBP in A was 53.3%; it is 83.3% in B; it is 80.0% in C. The difference for B and C compared with A was significant (P<0.05), C is low to B but no significance; and there was Nausea, loss of appetite, dry mouth, insomnia, etc. in B; there was no side effects in C. Conclusion:For patients with HBP and anxiety, Wuling capsule combined with amlodipine besylate is much better; and Wuling capsules has little side effects.