CAJ | 학술논문

目的:观察甘利欣注射液对类风湿关节炎患者转氨酶升高的治疗作用.方法:选择类风湿关节炎伴转氨酶升高患者80例,其中病情较重的40例为治疗组,病情较轻的40例为对照组,治疗组内服中药汤剂辨证论治,静滴甘利欣150mg/d.对照组仅内服中药汤剂辨证论治.治疗12d,观察治疗前后临床症状、转氨酶、CRP、ESR、RF 的变化.结果:治疗组和对照组治疗前后临床症状和转氨酶的变化均有明显改善,但治疗组改善程度,明显优于对照组,统计学处理有显著差异(P<0.05或 P<0.01).结论:甘利欣对 RA 伴转氨酶升高患者具有显著护肝降酶作用,对类风湿病情无不良影响.
목적:관찰감리흔주사액대류풍습관절염환자전안매승고적치료작용.방법:선택류풍습관절염반전안매승고환자80례,기중병정교중적40례위치료조,병정교경적40례위대조조,치료조내복중약탕제변증론치,정적감리흔150mg/d.대조조부내복중약탕제변증론치.치료12d,관찰치료전후림상증상、전안매、CRP、ESR、RF 적변화.결과:치료조화대조조치료전후림상증상화전안매적변화균유명현개선,단치료조개선정도,명현우우대조조,통계학처리유현저차이(P<0.05혹 P<0.01).결론:감리흔대 RA 반전안매승고환자구유현저호간강매작용,대류풍습병정무불량영향.
Objective: To observe therapeutic effect of Ganlixin injection for transaminase elevations in patients with rheumatoid arthritis (RA). Methods: 80 patients with RA associated elevated aminotransferases were selected, the serious condition of the 40 cases as the treatment group, 40 cases of less severe for the control group, the treatment group taken herbs decoction, the intravenous infusion of Ganlixin 150mg/day. The control group only taken herbs decoction, treatment for 12 days, the changes of clinical symptoms, transaminase, CRP, ESR, RF were observed before and after treatment. Results: Clinical symptoms and transaminase changes in the two groups before and after treatment were significantly improved, however, the degree of improvement of the treatment group was significantly better than that of the control group, statistically significant difference (P<0.05 or P<0.01). Conclusion: Ganlixin had the significant hepatoprotective JiangMei role, no adverse effects on rheumatoid situation.