CAJ | 학술논문

观察清身降糖颗粒和二甲双胍在对 IGT 患者临床症状、血糖、胰岛素水平、不良反应及糖尿病转化率等方面的差异.方法:将60例 IGT 患者随机分成清身降糖颗粒组30例和二甲双胍组30例.所有受试者在观察开始前均接受关于 IGT 方面的知识教育,并普及行为干预知识如合理饮食、运动疗法、心理疗法,观察时间为6个月.结果:①两组均能明显改善 IGT 患者临床症状、血糖、胰岛素水平(P<0.05);②清身降糖颗粒组在改善2hPG 和临床症状方面明显优于二甲双胍组(P<0.05);③清身降糖颗粒组无明显副作用;④清身降糖颗粒组转为正常糖耐量者9例,仍为 IGT 者21例;二甲双胍组转为正常糖耐量者8例,仍为 IGT 者20例,转为糖尿病者2 例;两组比较没有统计学意义;⑤治疗过程中除二甲双胍引起的副作用外,两组患者无其他不良反应的发生.结论:清身降糖颗粒在改善 IGT 患者的2hPG 和临床症状方面明显优于单独服用二甲双胍,且无二甲双胍的副作用.
관찰청신강당과립화이갑쌍고재대 IGT 환자림상증상、혈당、이도소수평、불량반응급당뇨병전화솔등방면적차이.방법:장60례 IGT 환자수궤분성청신강당과립조30례화이갑쌍고조30례.소유수시자재관찰개시전균접수관우 IGT 방면적지식교육,병보급행위간예지식여합리음식、운동요법、심리요법,관찰시간위6개월.결과:①량조균능명현개선 IGT 환자림상증상、혈당、이도소수평(P<0.05);②청신강당과립조재개선2hPG 화림상증상방면명현우우이갑쌍고조(P<0.05);③청신강당과립조무명현부작용;④청신강당과립조전위정상당내량자9례,잉위 IGT 자21례;이갑쌍고조전위정상당내량자8례,잉위 IGT 자20례,전위당뇨병자2 례;량조비교몰유통계학의의;⑤치료과정중제이갑쌍고인기적부작용외,량조환자무기타불량반응적발생.결론:청신강당과립재개선 IGT 환자적2hPG 화림상증상방면명현우우단독복용이갑쌍고,차무이갑쌍고적부작용.
Objective: To investigate the clinical effect of Qingshen Jiangtang granula and Metformin in IGT. Methods: 60 patients of IGT were randomly divided into two groups, 30 in each group. One group was treated with Qingshen Jiangtang granula and the other with Metformin. Results: The clinical symptoms, contents of blood sugar and insuline were improved in both groups (P<0.05). The Qingshen Jiangtang granula group had better effect in 2hPG and clinical symptoms (P<0.05), with no obvious side effects. 9 cases in the Qingshen Jiangtang granula group turned into normal, another 21 cases were still IGT, while in the Metformin group 8 cases turned into normal, 20 cases remained IGT and 2 cases turned into diabetes, with no significant differences between them. No side effects were detected besides that caused by Metformin. Conclusion: Qingshen Jiangtang granula had better effect than Metformin, with no side effects.