CAJ | 학술논문

目的:观察杀胚异位饮联合甲氨蝶呤、米非司酮保守治疗异位妊娠的临床效果.方法:55例异位妊娠患者被随机分为两组.对照组采用甲氨蝶呤50mg/m2,单次肌肉注射,米非司酮片50mg,空腹口服,每12h 1次,服2d,治疗组在上述治疗基础上,加用杀胚异位饮.在治疗第4d 和第7d 测血β-HCG,以后每隔3d 复查 1次.每周复查血常规、肝肾功、B 超,同时记录药物不良反应.结果:临床疗效治疗组疗效优于对照组,差异具有显著性(P<0.05);血β-HCG 下降至正常所需时间治疗组疗效优于对照组,差异具有显著性(P<0.05);两组盆腔包块消失时间治疗组疗效优于对照组,差异具有显著性(P<0.05);药物副反应治疗组疗效优于对照组,差异具有显著性(P<0.05).结论:杀胚异位饮联合甲氨蝶呤、米非司酮对治疗异位妊娠有较好的临床效果.
목적:관찰살배이위음연합갑안접령、미비사동보수치료이위임신적림상효과.방법:55례이위임신환자피수궤분위량조.대조조채용갑안접령50mg/m2,단차기육주사,미비사동편50mg,공복구복,매12h 1차,복2d,치료조재상술치료기출상,가용살배이위음.재치료제4d 화제7d 측혈β-HCG,이후매격3d 복사 1차.매주복사혈상규、간신공、B 초,동시기록약물불량반응.결과:림상료효치료조료효우우대조조,차이구유현저성(P<0.05);혈β-HCG 하강지정상소수시간치료조료효우우대조조,차이구유현저성(P<0.05);량조분강포괴소실시간치료조료효우우대조조,차이구유현저성(P<0.05);약물부반응치료조료효우우대조조,차이구유현저성(P<0.05).결론:살배이위음연합갑안접령、미비사동대치료이위임신유교호적림상효과.
Objective: To investigate the clinical effect of Shapei Yiwei decoction combined with amethopterin and mifepristone in treating eccyesis. Methods: 55 patients with eccyesis were randomly divided into two groups, 30 in the treated group and 25 in the control group. The control group was given amethopterin 50mg/m2 i.m. and mifepristone 50mg per 12 hours for 2 day. The treated group was given Shapei Yiwei decoction more. The content of β-HCG was detected 4 days and 7 days after the treatment. The routine items of blood, the functions of liver and kidney were detected every week. And the drug adverse reactions were observed as well. Results: The clinical effect of the treated group was better than the control group. The time of the treated group was shorter. The treated group had less side effetts. The @@@@differences between the two groups were significant. Conclusion: Shapei Yiwei decoction combined with amethopterin and mifepristone had notiable clinical efficacy in eccyesis.