CAJ | 학술논문

目的:探讨针刺对心理应激性勃起功能障碍(ED)大鼠勃起功能影响的作用机制.方法:应用悬吊水池法建立心理应激性勃起功能障碍大鼠模型30只,将制模成功的大鼠随机分为模型组(n=10)、针刺组(n=10),另设正常对照组(n=10).针刺组取“关元”、“三阴交”、“肾俞”穴施治,应用免疫组化 SP 法检测3组大鼠阴茎组织中神经型一氧化氮合酶(nNOS)的表达.结果:与模型组相比,针刺能明显提高针刺组大鼠的勃起次数(P<0.05),并提高大鼠阴茎组织中 nNOS 的表达(P<0.05).结论:针刺能明显增强心理应激性勃起功能障碍大鼠的勃起功能,其作用机制与大鼠阴茎组织中 nNOS 水平升高有关.
목적:탐토침자대심리응격성발기공능장애(ED)대서발기공능영향적작용궤제.방법:응용현조수지법건립심리응격성발기공능장애대서모형30지,장제모성공적대서수궤분위모형조(n=10)、침자조(n=10),령설정상대조조(n=10).침자조취“관원”、“삼음교”、“신유”혈시치,응용면역조화 SP 법검측3조대서음경조직중신경형일양화담합매(nNOS)적표체.결과:여모형조상비,침자능명현제고침자조대서적발기차수(P<0.05),병제고대서음경조직중 nNOS 적표체(P<0.05).결론:침자능명현증강심리응격성발기공능장애대서적발기공능,기작용궤제여대서음경조직중 nNOS 수평승고유관.
Objective:To explore the effect and mechanism of acupuncture on treating psychical erectile dysfunction (ED). Methods:30 ED rats were achieved by suspending in the pool. They were randomly divided into the model group and the treated group, 10 rats in each group. Another 10 rats were used in the control group. Apuncture were treated on “Guanyuan” , “Sanyinjiao”, “Shenyu” in the treated group. The nNOS expression was assayed by immunohistochemical methods. Results:Compared with the model group, acupuncture treatment significantly improved the the times of erectile in the treated group (P<0.05), and significantly increase the expression of nNOS in the penile tissue. Conclusion: Acupuncture can markedly improve the erectile function, and its mechanism was related to the higher expression of nNOS.