大理学院学报
大理學院學報
대이학원학보
JOURNAL OF DALI COLLEGE
2013年
3期
59-62
,共4页
大肠埃希菌%肺炎克雷伯杆菌%耐药性分析
大腸埃希菌%肺炎剋雷伯桿菌%耐藥性分析
대장애희균%폐염극뢰백간균%내약성분석
Escherichia coli%Klebsiella pneumoniae%resistance analysis
[摘要]:目的:对大理学院附属医院2011年至2012年临床分离的大肠埃希菌及肺炎克雷伯杆菌的耐药性进行分析,指导临床合理应用抗生素.方法:菌株分离及培养按常规方法进行,细菌鉴定采用VITET-2 Compact 60全自动微生物分析仪,药敏试验采用K-B法.结果:共收集标本183株,其中大肠埃希菌146株:口痰92株(63%)、分泌物17株(11.6%)、尿液16株(10.9%),脓液9株(6.1%),其他12株(8.2%);肺炎克雷伯杆菌37株:口痰27株(73%)、分泌物5株(13.5%)、脓液3株(8%)其他2株(5.4%).药敏试验结果显示:大肠埃希菌和肺炎克雷伯杆菌对头孢哌酮、阿米卡星、亚胺培南等耐药率较低,分别为10.3%、6.2%、2.7%和10.8%、13.5%、2.7%.结论:大肠埃希菌及肺炎克雷伯杆菌两年痰液中检出率呈上升趋势,对左氧氟沙星、头孢唑啉,氨曲南,头孢他啶等耐药率超过50%,特别是头孢他啶的耐药率相对于2008年显著升高,而对头孢哌酮、阿米卡星、亚胺培南等耐药性较低,临床应根据药敏实验合理选择抗生素.
[摘要]:目的:對大理學院附屬醫院2011年至2012年臨床分離的大腸埃希菌及肺炎剋雷伯桿菌的耐藥性進行分析,指導臨床閤理應用抗生素.方法:菌株分離及培養按常規方法進行,細菌鑒定採用VITET-2 Compact 60全自動微生物分析儀,藥敏試驗採用K-B法.結果:共收集標本183株,其中大腸埃希菌146株:口痰92株(63%)、分泌物17株(11.6%)、尿液16株(10.9%),膿液9株(6.1%),其他12株(8.2%);肺炎剋雷伯桿菌37株:口痰27株(73%)、分泌物5株(13.5%)、膿液3株(8%)其他2株(5.4%).藥敏試驗結果顯示:大腸埃希菌和肺炎剋雷伯桿菌對頭孢哌酮、阿米卡星、亞胺培南等耐藥率較低,分彆為10.3%、6.2%、2.7%和10.8%、13.5%、2.7%.結論:大腸埃希菌及肺炎剋雷伯桿菌兩年痰液中檢齣率呈上升趨勢,對左氧氟沙星、頭孢唑啉,氨麯南,頭孢他啶等耐藥率超過50%,特彆是頭孢他啶的耐藥率相對于2008年顯著升高,而對頭孢哌酮、阿米卡星、亞胺培南等耐藥性較低,臨床應根據藥敏實驗閤理選擇抗生素.
[적요]:목적:대대이학원부속의원2011년지2012년림상분리적대장애희균급폐염극뢰백간균적내약성진행분석,지도림상합리응용항생소.방법:균주분리급배양안상규방법진행,세균감정채용VITET-2 Compact 60전자동미생물분석의,약민시험채용K-B법.결과:공수집표본183주,기중대장애희균146주:구담92주(63%)、분비물17주(11.6%)、뇨액16주(10.9%),농액9주(6.1%),기타12주(8.2%);폐염극뢰백간균37주:구담27주(73%)、분비물5주(13.5%)、농액3주(8%)기타2주(5.4%).약민시험결과현시:대장애희균화폐염극뢰백간균대두포고동、아미잡성、아알배남등내약솔교저,분별위10.3%、6.2%、2.7%화10.8%、13.5%、2.7%.결론:대장애희균급폐염극뢰백간균량년담액중검출솔정상승추세,대좌양불사성、두포서람,안곡남,두포타정등내약솔초과50%,특별시두포타정적내약솔상대우2008년현저승고,이대두포고동、아미잡성、아알배남등내약성교저,림상응근거약민실험합리선택항생소.
@@@@Objective:To instruct the clinical medicine in Affiliated Hospital of Dali University by analyzing the resistance of Escherichia coli and Klebsiella pneumoniae from 2011 to 2012. Methods:Isolate and culture strains by using conventional methods, and identify the bacteria with VITET-2 Compact 60 automatic microbial analyzer and test the susceptibility through K-B. Results:In total 183 specimens, 146 of them were Escherichia coli:koutan 92(63%), secretions 17(11.6%), urine 16(10.9%), pus 9(6.1%2), other 12(8.2%);37 of them were Klebsiella pneumoniae:koutan 27(73%), secretions five(13.5%), pus 3(8%), other susceptibility test results:the resistance rates of Cefoperazone, Amikacin, Imipenem were lower, at 10.3%, 6.2%, 2.7%and 10.8%, 13.5%, 2.7%, respectively. Conclusion:The detection rate of Escherichia coli and Klebsiella pneumoniae in sputum is rising in these two years, and the resistance rates have been exceeded more than 50% of levofloxacin, cefazolin, aztreonam, ceftazidime, especially ceftazidimewas resistance rates is significantly elevated. However, resistance rates of cefoperazone, amikacin, imipenem are lower, so doctors should choose antibiotics based on susceptibility experiments.
