CAJ | 학술논문

目的:回顾性研究现代放射治疗在老年Ⅳ期直肠癌治疗中的应用价值.方法:2006年8月至2009年8月经病理学确诊的老年Ⅳ期直肠癌患者30例,接受三维适形放射治疗,转移灶照射总剂量62~66Gy/31~33F,放疗期间给予基础支持治疗;评估患者的治疗敏感性、近期疗效、中位无疾病进展时间(progression free survival,PFS)和不良反应.结果:老年Ⅳ期直肠癌采用三维适形放射治疗,其有效率达43%,疾病控制率为90%,PFS为8月;转移灶对放射治疗敏感,无明显副反应.结论:直肠癌转移灶对放射线敏感,现代放射治疗在老年Ⅳ期直肠癌治疗中具有重要临床应用价值.
목적:회고성연구현대방사치료재노년Ⅳ기직장암치료중적응용개치.방법:2006년8월지2009년8월경병이학학진적노년Ⅳ기직장암환자30례,접수삼유괄형방사치료,전이조조사총제량62~66Gy/31~33F,방료기간급여기출지지치료;평고환자적치료민감성、근기료효、중위무질병진전시간(progression free survival,PFS)화불량반응.결과:노년Ⅳ기직장암채용삼유괄형방사치료,기유효솔체43%,질병공제솔위90%,PFS위8월;전이조대방사치료민감,무명현부반응.결론:직장암전이조대방사선민감,현대방사치료재노년Ⅳ기직장암치료중구유중요림상응용개치.
Objective: To study the efficacy of modern radiation therapy in elderly patients with grade Ⅳrectal cancer. Methods: 30 cases of elderly grade Ⅳ rectal cancer from August 2006 to August 2009,confirmed by pathology, received three~dimensional conformal radiation therapy (3DCRT), with a total dose of 62~66Gy/31~33F to metastatic tumor,and with basic supportive care were retrospectively studied. The sensitivity of treatment、short~term efficacy、progression free survival (PFS)and adverse reactions were evaluated. Results: The response rate、disease control rate and PFS were 43%、90% and 8m,respetively;when three~dimensional conformal radiation therapy for elderly Ⅳ stage rectal cancer patients. The metastatic tumors were sensitive to radiation therapy with no serious side effects.Conclusion:The metastases of Elderly stage ⅣRectal Cancer are sensitive to radiation. Modern radiation therapy has important clinical value.