CAJ | 학술논문

利用麦苗对无机硒富集转化为有机硒,制备成冲剂,通过动物试验来观察其对小鼠免疫功能的调节作用.用富硒麦芽粉为原料制备成富硒麦芽冲剂,试验动物分3个剂量组(1.0、2.0、4.0 g/kg·BW),称取样品用蒸馏水混合,同时设蒸馏水对照组,各组灌胃量为每天0.2 mL,连续30 d.测小鼠细胞免疫与体液免疫相关指标,并对其进行统计分析.HC50试验高剂量组结果高于对照组(P<0.05),抗体生成试验的中、高剂量组抗体生成细胞数高于对照组(P<0.05);小鼠迟发性变态反应试验显示,高剂量组小鼠攻击前后足跖厚度差值高于对照组(P<0.05);NK细胞活性检测,中、高剂量组NK细胞活性高于对照组(P<0.05).提示富硒麦芽冲剂具有增强小鼠免疫力功能的作用.
이용맥묘대무궤서부집전화위유궤서,제비성충제,통과동물시험래관찰기대소서면역공능적조절작용.용부서맥아분위원료제비성부서맥아충제,시험동물분3개제량조(1.0、2.0、4.0 g/kg·BW),칭취양품용증류수혼합,동시설증류수대조조,각조관위량위매천0.2 mL,련속30 d.측소서세포면역여체액면역상관지표,병대기진행통계분석.HC50시험고제량조결과고우대조조(P<0.05),항체생성시험적중、고제량조항체생성세포수고우대조조(P<0.05);소서지발성변태반응시험현시,고제량조소서공격전후족척후도차치고우대조조(P<0.05);NK세포활성검측,중、고제량조NK세포활성고우대조조(P<0.05).제시부서맥아충제구유증강소서면역력공능적작용.
@@@@To investigate the Se-rich malt granules effects on immune function in mice, which the Se-rich malt was transformed from inorganic Se. Mice were randomly selected and divided into 3 groups:control group, Se-rich malt groups with the dose of 1.0,2.0,4.0 g/kg·BW by oral administration for 30 d respectively. The cellular immunity and humoral immunity of mice were tested. HC50 value of the high group mice increased (P<0.05), hemolytic antibody of high and middle groups were significantly increased markedly (P<0.05), the delayed type hypersensitivity (DTH) were better than that of the control group (P<0.05), NK cells activities of the high and middle groups were strengthened (P<0.05). Se-rich malt granules can promote mice immunity.