CAJ | 학술논문

探讨葡萄对断奶大鼠肠道自由基清除能力和抗氧化能力的影响.葡萄汁添加到基础日粮,连续28 d喂养断奶SD大鼠,测定体重增长率和肠道指数,血浆、肝脏及空肠中丙二醛(MDA)含量,以及过氧化氢酶(CAT)、超氧化物歧化酶(SOD)和诱导型一氧化氮合成酶(iNOS)的活性.在14 d与28 d,葡萄能显著提高断奶大鼠体重增长率,对其小肠指数没有显著影响.14 d时,葡萄组断奶大鼠血浆中SOD和MDA显著增加;28 d时断奶大鼠血浆中的MDA含量显著降低.14 d时,空肠iNOS活性显著降低.实验结果表明,葡萄可提高断奶大鼠肠道抗氧化能力.
탐토포도대단내대서장도자유기청제능력화항양화능력적영향.포도즙첨가도기출일량,련속28 d위양단내SD대서,측정체중증장솔화장도지수,혈장、간장급공장중병이철(MDA)함량,이급과양화경매(CAT)、초양화물기화매(SOD)화유도형일양화담합성매(iNOS)적활성.재14 d여28 d,포도능현저제고단내대서체중증장솔,대기소장지수몰유현저영향.14 d시,포도조단내대서혈장중SOD화MDA현저증가;28 d시단내대서혈장중적MDA함량현저강저.14 d시,공장iNOS활성현저강저.실험결과표명,포도가제고단내대서장도항양화능력.
@@@@To evaluate the effect of grape on the antioxidant of intestinal in the weaning rat. 32 Sprague-Dawley (SD) rats were randomLy grouped to receive the diets supplemented with grape juice or not, for 28 days. Rate of body weight and index of intestine, the activity of superoxide dismutase (SOD) and catalase (CAT), the concentration of malonaldehyde (MDA) of plasma, the activity of the SOD, CAT and induced-nitric oxide synthase (iNOS), and production of MDA of liver and jejunum in the weaning rat were determined. The rate of weight body for the weaning rats supplemented with grape was significantly increased compared with control group at 14d and 28 d. The activity of SOD and concentration of MDA in plasma were increased at 14 d and the concentration of MDA decreased at 28 d. The iNOS activity in jejunum for grape group was significantly decreased compared to control group at 14 d. Grape can increase the antioxidant capacity of intestinal in weaning rat.