中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
16期
2956-2960
,共5页
许东辉%李东原%李新颖%丁红月
許東輝%李東原%李新穎%丁紅月
허동휘%리동원%리신영%정홍월
生物材料%细胞外基质材料%胎儿%脐静脉%近胎盘段%远胎盘段%应力松弛%对比分析
生物材料%細胞外基質材料%胎兒%臍靜脈%近胎盤段%遠胎盤段%應力鬆弛%對比分析
생물재료%세포외기질재료%태인%제정맥%근태반단%원태반단%응력송이%대비분석
biomaterials%extracel ular matrix materials%fetus%umbilical cord vein%proximal placenta segment%distal placenta segment%stress relaxation%contrast analysis
背景:人脐静脉是动脉移植物的良好替代材料,在移植时除了考虑脐静脉与宿主动脉相匹配外,还应注意其顺应性.
目的:检测胎儿脐静脉近胎盘段和远胎盘段试样的应力松弛特性.
方法:取22-28岁、胎龄38-40周、自然分娩产妇的正常胎儿脐静脉近胎盘段和远胎盘段各10个试样,在电子万能实验机上进行应力松弛实验,在(36.5±0.5)℃的温度场下,以0.1%/s 的应变增加速度对试样施加应变,设定时间为7200 s.采集100个数据,采用归一化分析的方法计算两组试样的归一化应力松弛方程.
结果与结论:脐静脉近胎盘段组7200 s应力下降了0.275 MPa,脐静脉远胎盘段组7200 s应力下降了0.203 MPa,两组7200 s应力下降量差异有显著性意义(P<0.05).两组试样应力松弛曲线是以对数关系变化的,并且胎儿脐静脉近胎盘段和远胎盘段具有不同的应力松弛特性.
揹景:人臍靜脈是動脈移植物的良好替代材料,在移植時除瞭攷慮臍靜脈與宿主動脈相匹配外,還應註意其順應性.
目的:檢測胎兒臍靜脈近胎盤段和遠胎盤段試樣的應力鬆弛特性.
方法:取22-28歲、胎齡38-40週、自然分娩產婦的正常胎兒臍靜脈近胎盤段和遠胎盤段各10箇試樣,在電子萬能實驗機上進行應力鬆弛實驗,在(36.5±0.5)℃的溫度場下,以0.1%/s 的應變增加速度對試樣施加應變,設定時間為7200 s.採集100箇數據,採用歸一化分析的方法計算兩組試樣的歸一化應力鬆弛方程.
結果與結論:臍靜脈近胎盤段組7200 s應力下降瞭0.275 MPa,臍靜脈遠胎盤段組7200 s應力下降瞭0.203 MPa,兩組7200 s應力下降量差異有顯著性意義(P<0.05).兩組試樣應力鬆弛麯線是以對數關繫變化的,併且胎兒臍靜脈近胎盤段和遠胎盤段具有不同的應力鬆弛特性.
배경:인제정맥시동맥이식물적량호체대재료,재이식시제료고필제정맥여숙주동맥상필배외,환응주의기순응성.
목적:검측태인제정맥근태반단화원태반단시양적응력송이특성.
방법:취22-28세、태령38-40주、자연분면산부적정상태인제정맥근태반단화원태반단각10개시양,재전자만능실험궤상진행응력송이실험,재(36.5±0.5)℃적온도장하,이0.1%/s 적응변증가속도대시양시가응변,설정시간위7200 s.채집100개수거,채용귀일화분석적방법계산량조시양적귀일화응력송이방정.
결과여결론:제정맥근태반단조7200 s응력하강료0.275 MPa,제정맥원태반단조7200 s응력하강료0.203 MPa,량조7200 s응력하강량차이유현저성의의(P<0.05).량조시양응력송이곡선시이대수관계변화적,병차태인제정맥근태반단화원태반단구유불동적응력송이특성.
@@@@BACKGROUND:Human umbilical cord vein can serve as a good substitute for arterial grafts. Compliance of graft materials is a key problem during the transplantation expect for the matching between the umbilical cord vein and host’s artery. @@@@OBJECTIVE:To detect the stress relaxation properties of fetal umbilical vein samples proximal and distal to the placenta. @@@@METHODS:Fetal umbilical vein samples at the gestational age of 38-40 were taken from spontaneous delivery parturient women aged 22-28 years. Ten proximal placenta segments and 10 distal placenta segments were taken and placed on the electronic universal testing machine to do the stress relaxation test at (36.5±0.5) ℃. The strain was applied to the samples at a strain increases speed of 0.1%/s, and the setting time was 7 200 seconds. Total y 100 data were col ected;and then, the normalized analysis method was employed to calculate the normalized stress relaxation equation. @@@@RESULTS AND CONCLUSION:The stress at 7 200 seconds was decreased by 0.275 MPa in the proximal placenta segment group and 0.203 MPa in the distal placenta segment group. There was a significant difference between the two segment samples (P<0.05). The stress relaxation curves of the two groups were changed with logarithmic relationship, and the proximal placenta segment and the distal placenta segment of fetal umbilical cord vein had different stress relaxation properties.