CAJ | 학술논문

背景:抗菌剂如纳米载银、季胺盐、磷酸钙等,具有良好的抗菌作用,能对口腔中常见致病菌的生长起到抑制作用,将抗菌剂作为填料加入复合树脂,制成抗菌性复合树脂,是当前研究的一个热点. 目的:综述近年国内外关于抗菌性复合树脂的研究情况. 方法:以“复合树脂,抗菌剂,银离子,季胺盐,磷酸钙”为中文关键词,以“composite resin, antibacterial agent, silver ion, amine salt, calcium phosphate”为英文关键词,采用计算机检索1995年1月至2012年5月中国知网数据库 CNKI、PubMed 数据库和维普中文科技期刊数据库、万方数据库、Web of Science 期刊引文索引数据库及Nature数据库有关抗菌性复合树脂的文献. 结果与结论:抗菌剂分为天然、有机、无机、有机高分子抗菌剂.目前研究较多的有纳米载银抗菌性复合树脂、季铵盐抗菌性复合树脂、纳米磷酸钙抗菌性复合树脂等.体内外实验表明,抗菌剂的加入使复合树脂具有较强的抗菌性能,可阻断细菌的生长过程,进而减少继发龋的发生,延长修复体的寿命,且不改变复合树脂的理化性质.最新的研究中将多种不同性质的抗菌剂混合加入复合树脂中得到了具有更强抗菌性、机械性能的抗菌性复合树脂,这也将成为今后研究新型抗菌性复合树脂的重要方向.
배경:항균제여납미재은、계알염、린산개등,구유량호적항균작용,능대구강중상견치병균적생장기도억제작용,장항균제작위전료가입복합수지,제성항균성복합수지,시당전연구적일개열점. 목적:종술근년국내외관우항균성복합수지적연구정황. 방법:이“복합수지,항균제,은리자,계알염,린산개”위중문관건사,이“composite resin, antibacterial agent, silver ion, amine salt, calcium phosphate”위영문관건사,채용계산궤검색1995년1월지2012년5월중국지망수거고 CNKI、PubMed 수거고화유보중문과기기간수거고、만방수거고、Web of Science 기간인문색인수거고급Nature수거고유관항균성복합수지적문헌. 결과여결론:항균제분위천연、유궤、무궤、유궤고분자항균제.목전연구교다적유납미재은항균성복합수지、계안염항균성복합수지、납미린산개항균성복합수지등.체내외실험표명,항균제적가입사복합수지구유교강적항균성능,가조단세균적생장과정,진이감소계발우적발생,연장수복체적수명,차불개변복합수지적이화성질.최신적연구중장다충불동성질적항균제혼합가입복합수지중득도료구유경강항균성、궤계성능적항균성복합수지,저야장성위금후연구신형항균성복합수지적중요방향.
@@@@BACKGROUND:Antibacterial agents with good antibacterial effects, such as nano silver, amine salt, and calcium phosphate, have a growth inhibition on common pathogenic bacteria in the mouth. Recently, it is a hot issue to make antimicrobial composite resins by adding the antibacterial agents to the composite resin. @@@@OBJECTIVE:To summarize recent studies on antimicrobial composite resin. @@@@METHODS:Databases of CNKI, PubMed, Wanfang, VIP, Web of Science, and Nature from January 1995 to May 2012 were searched by computer with key words of“composite resin, antibacterial agent, silver ion, amine salt, calcium phosphate”both in Chinese and English. Literatures concerning antibacterial agents and antimicrobial composite resin were included, and repetitive research was excluded. @@@@RESULTS AND CONCLUSION:Antibacterial agents are classified into natural, organic, inorganic, polymer agents. Currently, antimicrobial composite resins carrying nano sliver, amine salt, and calcium phosphate are often reported. The vivo and vitro experiments show that the composite resin with antibacterial agents has good antibacterial properties, which can inhibit the growth of bacteria, reduce the occurrence of recurrent caries, and prolong the in-service life of the prosthesis, and its physical and chemical properties have no apparent changes. In the latest study, the composite resin has better antibacterial properties and mechanical functions by addition with al kinds of antibacterial agents, which wil be the main direction of studying the novel antimicrobial composite resin in the future.