CAJ | 학술논문

目的回顾性分析83例采用液基薄层细胞学(TCT)法检测的非典型鳞状细胞(ASC)阳性以上病变,并经阴道镜检加病理组织学检测患者为阳性的相关资料,分析TCT技术在筛选ASC阳性以上病变中的临床价值.方法选择我院2009-01—2011-07就诊的经TCT检查结果为ASC阳性以上,并经阴道镜检加病理组织学检测为阳性的妇女83例,以阴道镜活检组织病理诊断为标准,TCT结果与病理组织学诊断进行对照.分析比较细胞学诊断为ASC阳性以上的病例经阴道镜诊断,阴道镜下活检与病理组织学诊断结果之间的关系.结果 ASC 32例经阴道镜检病理组织学诊断CIN者为18例,诊断符合率为56%;30例LSIL经阴道镜检病理组织学诊断为CIN及以上者为24例,诊断符合率为80%;21例HSIL经阴道镜检病理组织学诊断为CIN者21例,诊断符合率为100%.TCT与阴道镜检病理组织学诊断符合率平均为79%.结论在TCT检测中ASC-US阳性以上的病例发生宫颈癌前病变率是较高的,运用高效合理规范化的筛查,能有效地降低宫颈癌的发病率和病死率.
목적회고성분석83례채용액기박층세포학(TCT)법검측적비전형린상세포(ASC)양성이상병변,병경음도경검가병리조직학검측환자위양성적상관자료,분석TCT기술재사선ASC양성이상병변중적림상개치.방법선택아원2009-01—2011-07취진적경TCT검사결과위ASC양성이상,병경음도경검가병리조직학검측위양성적부녀83례,이음도경활검조직병리진단위표준,TCT결과여병리조직학진단진행대조.분석비교세포학진단위ASC양성이상적병례경음도경진단,음도경하활검여병리조직학진단결과지간적관계.결과 ASC 32례경음도경검병리조직학진단CIN자위18례,진단부합솔위56%;30례LSIL경음도경검병리조직학진단위CIN급이상자위24례,진단부합솔위80%;21례HSIL경음도경검병리조직학진단위CIN자21례,진단부합솔위100%.TCT여음도경검병리조직학진단부합솔평균위79%.결론재TCT검측중ASC-US양성이상적병례발생궁경암전병변솔시교고적,운용고효합리규범화적사사,능유효지강저궁경암적발병솔화병사솔.
Objective To probe into the clinical value of TC T in screening A SC positive lesions w ith a retrospective analysis of 83 cases of using TC T to screen A SC positive lesions,and by colposcopy pathological detection in positive patients for relevant inform a-tion.Methods 83 w om en in our hospital from 2009 January to 2011 July w ho w ere diagnosed w ith A SC positive by TC T and also positive by colposcopy and pathological detection w ere treated w ith the standard of colposcopy biopsy hisopathology diagnosis,TC T re-sults in contrast w ith histodiagnosis.The relation betw een the diagnosis of A SC positive by colposcopy,A nalysis and com parison of cy-tology in the diagnosis of A SC positive over the case by colposcopy,colposcoped biopsy and pathologic histology w as analyzed.Results 18 out of 32 patients w ith A SC by colposcopy pathological detection w ere diagnosed w ith C IN ,the diagnostic accordance rate w as 56% ;24 out of 30 patients w ith LSIL by colposcopy pathological detection w ere diagnosed w ith C IN ,the diagnostic accordance rate w as 80% ;21 out of 21 patients w ith H SIL by colposcopy pathological detection w ere diagnosed w ith C IN ,the diagnosis accordance rate w as 100% .The average diagnosis accordance rate of TC T and colposcopy pathological detection w as 79% .Conclusion There is a high rate of precancerous lesions of uterine cervix am ong A SC-U S positive in TC T screening,and through efficient and norm alized screen-ing,the incidence and case fatality rate of cervical cancer can be effectively reduced.