中国医疗前沿
中國醫療前沿
중국의료전연
CHINA HEALTHCARE INNOVATION
2013年
8期
9-10
,共2页
脑梗死%脑微出血%磁共振成像%危险因素
腦梗死%腦微齣血%磁共振成像%危險因素
뇌경사%뇌미출혈%자공진성상%위험인소
Brain infarction%Cerebral microbleeds%Magnetic resonance imaging%Risk factors
目的了解急性脑梗死患者脑微出血(CMB)的发生率,分析其危险因素.方法选择2008年3月-2012年3月住院的急性脑梗死患者122例,行MRI磁敏感加权成像,根据有无CMB分为两组,对其一般临床资料和临床生化指标进行比较,探讨急性脑梗死合并CMB的相关危险因素;根据CMB的程度分为三组,分析颈动脉内膜增厚与CMB程度之间的关系.结果CMB组血清HDL水平显著性高于非CMB组(P<0.05),LDL水平显著性低于非CMB组(P<0.05).年龄、高血压、脑卒中史、吸烟史在CMB组中的比例显著性高于非CMB组,差异有统计学意义(P<0.05).CMB患者颈动IMT异常率显著性高于无CMB组(χ2=7.05,P<0.05),并且在轻、中、重三组中IMT异常率也具有显著差异(χ2=8.83,P=0.02).结论在急性脑梗死患者中,CMB发生与年龄、高血压、脑卒中史、吸烟史、颈动脉内膜增厚、血清HDL及LDL水平相关.
目的瞭解急性腦梗死患者腦微齣血(CMB)的髮生率,分析其危險因素.方法選擇2008年3月-2012年3月住院的急性腦梗死患者122例,行MRI磁敏感加權成像,根據有無CMB分為兩組,對其一般臨床資料和臨床生化指標進行比較,探討急性腦梗死閤併CMB的相關危險因素;根據CMB的程度分為三組,分析頸動脈內膜增厚與CMB程度之間的關繫.結果CMB組血清HDL水平顯著性高于非CMB組(P<0.05),LDL水平顯著性低于非CMB組(P<0.05).年齡、高血壓、腦卒中史、吸煙史在CMB組中的比例顯著性高于非CMB組,差異有統計學意義(P<0.05).CMB患者頸動IMT異常率顯著性高于無CMB組(χ2=7.05,P<0.05),併且在輕、中、重三組中IMT異常率也具有顯著差異(χ2=8.83,P=0.02).結論在急性腦梗死患者中,CMB髮生與年齡、高血壓、腦卒中史、吸煙史、頸動脈內膜增厚、血清HDL及LDL水平相關.
목적료해급성뇌경사환자뇌미출혈(CMB)적발생솔,분석기위험인소.방법선택2008년3월-2012년3월주원적급성뇌경사환자122례,행MRI자민감가권성상,근거유무CMB분위량조,대기일반림상자료화림상생화지표진행비교,탐토급성뇌경사합병CMB적상관위험인소;근거CMB적정도분위삼조,분석경동맥내막증후여CMB정도지간적관계.결과CMB조혈청HDL수평현저성고우비CMB조(P<0.05),LDL수평현저성저우비CMB조(P<0.05).년령、고혈압、뇌졸중사、흡연사재CMB조중적비례현저성고우비CMB조,차이유통계학의의(P<0.05).CMB환자경동IMT이상솔현저성고우무CMB조(χ2=7.05,P<0.05),병차재경、중、중삼조중IMT이상솔야구유현저차이(χ2=8.83,P=0.02).결론재급성뇌경사환자중,CMB발생여년령、고혈압、뇌졸중사、흡연사、경동맥내막증후、혈청HDL급LDL수평상관.
Objective To investigate the incidence of cerebral microbleeds(CMB) in patients with acute cerebral infarction and analyze its risk factors. Methods 122 patients with acute cerebral infarction admitted to our hospital from March 2008 to March 2012 were divided into CMB group(n=51) and non-CMB group(n=71) according to their MRI susceptibility-weighted imaging. General clinical data and biochemical variables were compared between two groups to explore relative risk factors of CMB. The patients were divided into three groups according to the extent of the CMB, and the relationship between carotid IMT level and the degree of CMB were analysised. Results The LDL levels were significantly lower while the HDL level was significantly higher in CMB group than non-CMB group(P<0.05). The proportion of age, hypertension, stroke history and history of smoking in the CMB groups were significantly higher than the non-CMB group(P<0.05). The abnormal rate of IMT in CMB group were significantly higher than the non-CMB group(χ2=7.05, P<0.05), and The abnormal rate of IMT among mild, moderate and severe CMB groups also have a significant difference(χ2=8.83, P=0.02). Conclusion Age, hypertension, stroke history, smoking history, intimal thickening in the carotid artery, serum HDL and LDL levels are all risk factors for CMBs.
