CAJ | 학술논문

目的探讨丝裂霉素C在治疗翼状胬肉中的治疗效果.方法对382例(400眼)采用两种不同术式分两组行手术治疗.Ⅰ组:翼状胬肉切除术+自体角膜缘干细胞移植术;Ⅱ组:翼状胬肉切除术+自体角膜缘干细胞移植术+丝裂霉素C.经过6个月~5年的对比观察.结果两种术式比较:翼状胬肉切除术+自体角膜缘干细胞移植术119眼,治愈104眼,复发15眼,复发率12.6%;翼状胬肉切除术+自体角膜缘干细胞移植术+丝裂霉素C手术281眼,治愈276眼,复发5眼,复发率1.8%.结论翼状胬肉切除术+自体角膜缘干细胞移植术+丝裂霉素C治疗翼状胬肉复发率明显低于翼状胬肉切除术+自体角膜缘干细胞移植术,且术后角、结膜上皮修复快,视力恢复好.
목적탐토사렬매소C재치료익상노육중적치료효과.방법대382례(400안)채용량충불동술식분량조행수술치료.Ⅰ조:익상노육절제술+자체각막연간세포이식술;Ⅱ조:익상노육절제술+자체각막연간세포이식술+사렬매소C.경과6개월~5년적대비관찰.결과량충술식비교:익상노육절제술+자체각막연간세포이식술119안,치유104안,복발15안,복발솔12.6%;익상노육절제술+자체각막연간세포이식술+사렬매소C수술281안,치유276안,복발5안,복발솔1.8%.결론익상노육절제술+자체각막연간세포이식술+사렬매소C치료익상노육복발솔명현저우익상노육절제술+자체각막연간세포이식술,차술후각、결막상피수복쾌,시력회복호.
Objective Analyze the clinical efficacy of surgical method to treat pterygium by pterygium excision with limbal autograft transplantation with mitomycin C in the operation. Methods 382 (400 eyes)pterygium patients admitted in our hospital, according to different surgical methods were divided into two groups:Ⅰgroup:pterygium excision combined with limbal autograft transplantation,Ⅱgroup:pterygium excision with limbal autograft transplantation with mitomycin C in the operation, Followed up for 6 months to 36 months.Record postoperative recurrence of pterygium, corneal epithelial healing time and postoperative visual acuity, Statistical analysis of differences results of each surgical method. Results The comparison of the recurrence rate of different pterygium group:Ⅰgroup (119 eyes) had 15 eyes recurrence ,the recurrence rate was 12.6%;Ⅱgroup (281 eyes) had 5 eye recurrence, the recurrence rate of 1.8%. After statistical analysis, the recurrence rate among the two groups has significant difference. Conclusions Pterygium excision with limbal autograft transplantation with mitomycin C in the operation is a better treatment to lower the recurrence rate of pterygium and better improvement visual acuity and corneal epithelial repair.