CAJ | 학술논문

目的探讨布地奈德联合沙丁胺醇、沐舒坦雾化吸入治疗慢性阻塞性肺病(COPD)急性加重期的临床效果.方法选择我院2009年1月至2012年8月收治的85例COPD急性加重期患者,将其随机分为治疗组和对照组,对照组采用常规治疗,治疗组在对照组的基础上采用布地奈德联合雾化吸入治疗.比较两组患者的临床疗效、肺功能情况、治疗前后的血气指标变化以及病情恶化次数和住院次数及不良反应进行比较分析.结果治疗组的总有效率为显著高于对照组的,P<0.05.且治疗组治疗后的肺功能情况、治疗前后的血气指标变化均显著优于对照组,P<0.05.结论布地奈德混悬液联合沙丁胺醇、沐舒坦治疗COPD急性加重期,能够明显缓解患者的症状,改善患者肺功能和血气指标.疗效可靠,值得临床推广应用.
목적탐토포지내덕연합사정알순、목서탄무화흡입치료만성조새성폐병(COPD)급성가중기적림상효과.방법선택아원2009년1월지2012년8월수치적85례COPD급성가중기환자,장기수궤분위치료조화대조조,대조조채용상규치료,치료조재대조조적기출상채용포지내덕연합무화흡입치료.비교량조환자적림상료효、폐공능정황、치료전후적혈기지표변화이급병정악화차수화주원차수급불량반응진행비교분석.결과치료조적총유효솔위현저고우대조조적,P<0.05.차치료조치료후적폐공능정황、치료전후적혈기지표변화균현저우우대조조,P<0.05.결론포지내덕혼현액연합사정알순、목서탄치료COPD급성가중기,능구명현완해환자적증상,개선환자폐공능화혈기지표.료효가고,치득림상추엄응용.
Objective To observe the clinical efficacy of inhalation treatment with budesonide and salbutamol and salbutamol combination for acute exacerbation of chronic bstructive pulmonary disease. Methods We selected 90 cases of AECOPD between Jan.2009 and August .2012,and classified them into treatment groupand observation group.Treatment effects,pulmonary function, treatment changes and blood gas before and after the exacerbation frequency and hospitalization and adverse effects were compared and analyzed. Results The total effective rate of the observation group was which was significantly higher than the, P<0.05.And the observation group, lung function after treatment, treatment before and after the deterioration of blood gas changes were significantly better than the control group, P<0.05.Conclusion Inhalation treatment with budesonide and salbutamol and mucosolvan combination for patients with AECOPD can relieve symptoms and improve function and blood gas sub-index, reduce relapse.so it is worthy of promoting in the clinical application