CAJ | 학술논문

目的观察复方丹参注射液联合化疗对中晚期胃癌患者疗效、生活质量及不良反应的影响.方法78例中晚期非小细胞胃癌患者随机分为丹参注射液化疗、单纯化疗两组,观察组(39例)采用复方丹参注射液加DCF方案[多西他赛(DTX)+顺铂(DDP)+5-氟尿嘧啶(5-Fu)]治疗,对照组(39例)采用单纯DCF方案化疗.结果观察组和对照组总有效率分别为59.0%和51.3%(P<0.05),观察组毒副反应如血色素、白细胞及血小板的降低及恶心、呕吐等轻于对照组(P<0.05).结论复方丹参液能够提高DCF化疗的有效率,减轻化疗某些不良反应,值得进一步研究应用.
목적관찰복방단삼주사액연합화료대중만기위암환자료효、생활질량급불량반응적영향.방법78례중만기비소세포위암환자수궤분위단삼주사액화료、단순화료량조,관찰조(39례)채용복방단삼주사액가DCF방안[다서타새(DTX)+순박(DDP)+5-불뇨밀정(5-Fu)]치료,대조조(39례)채용단순DCF방안화료.결과관찰조화대조조총유효솔분별위59.0%화51.3%(P<0.05),관찰조독부반응여혈색소、백세포급혈소판적강저급악심、구토등경우대조조(P<0.05).결론복방단삼액능구제고DCF화료적유효솔,감경화료모사불량반응,치득진일보연구응용.
Objective Effect of Compound Danshen injection combined with chemotherapy on advanced gastric cancer patients, quality of life and adverse effects.Methods In 78 cases of advanced non small cell cancer patients were randomLy divided into Salvia miltiorrhiza injection chemotherapy, chemotherapy alone in two groups, The observation group (39 cases) by compound Danshen injection combined with DCF regimen [docetaxel (DTX)+cisplatin (DDP)+5-Fu (5-Fu )] treatment, the control group (39 cases) treated by chemotherapy of DCF regimen.Results The observation group and the control group, the total effective rates were 67.4%and 43.2%(P<0.05), the observation group side reactions such as hemoglobin, white blood cells and platelets to reduce nausea, vomiting and lighter than the control group (P<0.05).Conclusion Compound Danshen liquid can improve the efficiency of DCF chemotherapy, alleviating some adverse reactions, worthy of further research and application.