CAJ | 학술논문

磷脂酰肌醇蛋白多糖-3(glypican-3, GPC3)是继AFP之后发现的一个新的肝细胞癌标志物.随着对GPC3研究的不断深入,发现它不但在肝细胞癌组织中有表达而且在血清中同样有表达.GPC3对HCC诊断的敏感性和特异性较高,尤其在肿瘤发生的早期,具有极大的临床应用价值,为早期HCC的诊断带来了希望.
린지선기순단백다당-3(glypican-3, GPC3)시계AFP지후발현적일개신적간세포암표지물.수착대GPC3연구적불단심입,발현타불단재간세포암조직중유표체이차재혈청중동양유표체.GPC3대HCC진단적민감성화특이성교고,우기재종류발생적조기,구유겁대적림상응용개치,위조기HCC적진단대래료희망.
@@@@ Glypican-3(GPC3) was confirmed to be a novel tumor marker for hepatocellular carcinoma(HCC) besides alpha-fetoprotein(AFP). With the constant deepening of GPC3 research, it was found not only in tissues of patients with HCC but also in the serum. In the diagnosis of HCC, there were higher sensitivity and specificity, especially in the early stage, which had great value in clinical application, and bring new hope for the diagnosis of HCC.