中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
21期
3893-3900
,共8页
李洪洋%钟丽芳%刘兵%蔡鸿丹
李洪洋%鐘麗芳%劉兵%蔡鴻丹
리홍양%종려방%류병%채홍단
生物材料%组织工程口腔材料%金属烤瓷冠%钴铬合金%银钯合金%牙周指数%牙周致病菌%省级基金
生物材料%組織工程口腔材料%金屬烤瓷冠%鈷鉻閤金%銀鈀閤金%牙週指數%牙週緻病菌%省級基金
생물재료%조직공정구강재료%금속고자관%고락합금%은파합금%아주지수%아주치병균%성급기금
biomaterials%tissue-engineered oral materials%porcelain-fused-to-metal crown%cobalt-chromium al oy%silver-pal adium al oy%periodontal index%periodontopathic bacteria%provincial grants-supported paper
背景:金属烤瓷全冠是修复牙体缺损的最常用方法,牙周问题是导致修复失败的最常见原因.目的:评价钴铬合金和银钯合金作为烤瓷冠内冠材料对牙周组织的影响.方法:选择采用钴铬合金和银钯合金烤瓷冠修复患者75例,189颗患牙,其中106颗采用钯合金烤瓷冠修复体,83颗应用钴铬合金修复体.于修复前后临床对比患牙龈沟出血指数、龈沟液量、龈沟液中与炎症相关的细胞因子白细胞介素1β和肿瘤坏死因子α浓度,以及龈沟液中牙龈卟啉单胞菌、伴放线嗜血杆菌、福赛斯坦纳菌等3种细菌检出率的变化.结果与结论:①与修复前比较,钴铬合金烤瓷冠修复12个月后,患牙龈沟出血指数和龈沟液量、龈沟液中细胞因子白细胞介素1β、肿瘤坏死因子α水平及龈沟液中牙龈卟啉单胞菌、福赛斯坦纳菌检出率升高(P <0.05或P﹤0.01),伴放线嗜血杆菌检出率无明显变化(P >0.05).②与修复前比较,银钯合金烤瓷冠修复12个月后,龈沟出血指数和龈沟液量升高(P <0.05),龈沟液中细胞因子白细胞介素1β、肿瘤坏死因子α水平及3种细菌检出率无明显变化(P >0.05).表明两种材料的烤瓷冠对患牙牙周组织均有影响,其中银钯合金影响较小,钴铬合金影响较大.
揹景:金屬烤瓷全冠是脩複牙體缺損的最常用方法,牙週問題是導緻脩複失敗的最常見原因.目的:評價鈷鉻閤金和銀鈀閤金作為烤瓷冠內冠材料對牙週組織的影響.方法:選擇採用鈷鉻閤金和銀鈀閤金烤瓷冠脩複患者75例,189顆患牙,其中106顆採用鈀閤金烤瓷冠脩複體,83顆應用鈷鉻閤金脩複體.于脩複前後臨床對比患牙齦溝齣血指數、齦溝液量、齦溝液中與炎癥相關的細胞因子白細胞介素1β和腫瘤壞死因子α濃度,以及齦溝液中牙齦卟啉單胞菌、伴放線嗜血桿菌、福賽斯坦納菌等3種細菌檢齣率的變化.結果與結論:①與脩複前比較,鈷鉻閤金烤瓷冠脩複12箇月後,患牙齦溝齣血指數和齦溝液量、齦溝液中細胞因子白細胞介素1β、腫瘤壞死因子α水平及齦溝液中牙齦卟啉單胞菌、福賽斯坦納菌檢齣率升高(P <0.05或P﹤0.01),伴放線嗜血桿菌檢齣率無明顯變化(P >0.05).②與脩複前比較,銀鈀閤金烤瓷冠脩複12箇月後,齦溝齣血指數和齦溝液量升高(P <0.05),齦溝液中細胞因子白細胞介素1β、腫瘤壞死因子α水平及3種細菌檢齣率無明顯變化(P >0.05).錶明兩種材料的烤瓷冠對患牙牙週組織均有影響,其中銀鈀閤金影響較小,鈷鉻閤金影響較大.
배경:금속고자전관시수복아체결손적최상용방법,아주문제시도치수복실패적최상견원인.목적:평개고락합금화은파합금작위고자관내관재료대아주조직적영향.방법:선택채용고락합금화은파합금고자관수복환자75례,189과환아,기중106과채용파합금고자관수복체,83과응용고락합금수복체.우수복전후림상대비환아간구출혈지수、간구액량、간구액중여염증상관적세포인자백세포개소1β화종류배사인자α농도,이급간구액중아간계람단포균、반방선기혈간균、복새사탄납균등3충세균검출솔적변화.결과여결론:①여수복전비교,고락합금고자관수복12개월후,환아간구출혈지수화간구액량、간구액중세포인자백세포개소1β、종류배사인자α수평급간구액중아간계람단포균、복새사탄납균검출솔승고(P <0.05혹P﹤0.01),반방선기혈간균검출솔무명현변화(P >0.05).②여수복전비교,은파합금고자관수복12개월후,간구출혈지수화간구액량승고(P <0.05),간구액중세포인자백세포개소1β、종류배사인자α수평급3충세균검출솔무명현변화(P >0.05).표명량충재료적고자관대환아아주조직균유영향,기중은파합금영향교소,고락합금영향교대.
@@@@BACKGROUND: Metal porcelain crown is the most commonly used method of repair of dental defects, and periodontal problems are the most common causes of repair failure. OBJECTIVE: To evaluate the influence of cobalt-chromium al oy and silver-pal adium al oy as the materials of inner crown on periodontal tissue. METHODS: Total y 189 clinical diseased teeth from 75 patients were chosen in this study. 106 teeth were repaired with cobalt-chromium al oy porcelain crown, and 83 were repaired with silver-pal adium al oy porcelain crown. The changes in periodontal sulcus bleeding index and amount of gingival crevicular fluid were observed. Interleukin-1 beta, tumor necrosis factor alpha and the positive rates of Porphyromonas gingivalis, Actinobacil us actinomycetemcomitans, Tannerel a forsythia in the gingival crevicular fluid were detected. RESULTS AND CONCLUSION: In the cobalt-chromium alloy porcelain crown group, there were significant differences in periodontal sulcus bleeding index, the amount of gingival crevicular fluid, interleukin-1 beta, and tumor necrosis factor alpha as well as the positive rates of Porphyromonas gingivalis and Tannerella forsythia in the gingival crevicular fluid prior to and 12 months post-restoration (P < 0.05), while there was no significant difference in the positive rate of Actinobacillus actinomycetemcomitans (P > 0.05). In the silver-palladium alloy porcelain crown group, there were significant differences in periodontal sulcus bleeding index and the amount of gingival crevicular fluid (P < 0.05), but no differences in interleukin-1 beta, tumor necrosis factor alpha and the positive rates of Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Tannerella forsythia in the gingival crevicular fluid prior to and 12 months post-restoration (P > 0.05). The cobalt-chromium alloy porcelain crown may have an adverse effect on periodontal tissue to a certain degree, while the silver-palladium alloy is an ideal substrate material of porcelain fused to metal crown.
