中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
5期
850-851
,共2页
膝骨性关节炎%虎力散胶囊%外敷
膝骨性關節炎%虎力散膠囊%外敷
슬골성관절염%호력산효낭%외부
Knee osteoarthritis%Hulisan capsul%External application
目的:观察中药虎力散胶囊外敷治疗膝骨性关节炎(KOA)的临床疗效与安全性.方法:采用随机对照研究方法,将64例KOA患者随机分为两组,即对照组(32例)和治疗组(32例),两组均给予硫酸氨基葡萄糖胶囊口服,在此基础上治疗组给予虎力散胶囊外敷,对照组给予扶他林乳剂外用,疗程4周,观察两组患者治疗前后症状及体征的变化.结果:治疗4周后,两组患者VAS评分和关节功能评分较治疗前均有明显改善(P均<0.05),且治疗组改善明显优于对照组(P<0.05),两组治疗前后临床疗效比较治疗组也明显优于对照组(P<0.05),两组治疗期间均无明显不良反应发生.结论:虎力散胶囊外敷治疗膝骨性关节炎能明显减轻关节肿胀疼痛症状,改善关节功能,具有良好的临床疗效,且安全性较高,值得临床推广应用.
目的:觀察中藥虎力散膠囊外敷治療膝骨性關節炎(KOA)的臨床療效與安全性.方法:採用隨機對照研究方法,將64例KOA患者隨機分為兩組,即對照組(32例)和治療組(32例),兩組均給予硫痠氨基葡萄糖膠囊口服,在此基礎上治療組給予虎力散膠囊外敷,對照組給予扶他林乳劑外用,療程4週,觀察兩組患者治療前後癥狀及體徵的變化.結果:治療4週後,兩組患者VAS評分和關節功能評分較治療前均有明顯改善(P均<0.05),且治療組改善明顯優于對照組(P<0.05),兩組治療前後臨床療效比較治療組也明顯優于對照組(P<0.05),兩組治療期間均無明顯不良反應髮生.結論:虎力散膠囊外敷治療膝骨性關節炎能明顯減輕關節腫脹疼痛癥狀,改善關節功能,具有良好的臨床療效,且安全性較高,值得臨床推廣應用.
목적:관찰중약호력산효낭외부치료슬골성관절염(KOA)적림상료효여안전성.방법:채용수궤대조연구방법,장64례KOA환자수궤분위량조,즉대조조(32례)화치료조(32례),량조균급여류산안기포도당효낭구복,재차기출상치료조급여호력산효낭외부,대조조급여부타림유제외용,료정4주,관찰량조환자치료전후증상급체정적변화.결과:치료4주후,량조환자VAS평분화관절공능평분교치료전균유명현개선(P균<0.05),차치료조개선명현우우대조조(P<0.05),량조치료전후림상료효비교치료조야명현우우대조조(P<0.05),량조치료기간균무명현불량반응발생.결론:호력산효낭외부치료슬골성관절염능명현감경관절종창동통증상,개선관절공능,구유량호적림상료효,차안전성교고,치득림상추엄응용.
@@@@Objective:To observe efficacy and safety of the traditional Chinese medicine Hulisan Capsule on the treatment of knee osteoarthritis.Methods:64 patients with KOA were randomly divided into two groups, namely control group ( 32 cases) and treatment group ( 32 cases), two groups were treated with glucosamine sulfate capsule, on this basis, the treatment group was given Hulisan capsule for external application, the control group was given diclofenac emulsion for external application,the course of treatment was 4 weeks, to observe the changes of symptoms and signs of the two groups of patients before and after treatment. Results:After 4 weeks treatment, VAS score and the score of joint function of two groups were significantly improved (P<0.05) compared with those before treatment, and those of the treatment group were better than control group ( P<0.05 ), the clinical effect of the treatment group was significantly better than that of control group. No obvious adverse reactions were found during treatment.Conclusion:Hulisan Capsule can significantly reduce the joint swelling and pain, improve joint function, has a good clinical effect, and high security, is worthy of clinical application.