CAJ | 학술논문

目的:总结我院近3年来儿童抗感染药物不良反应特征,为临床合理用药提供理论依据.方法:对我院2010年~2012年158例儿童应用抗菌药物引起的不良反应进行分析,从患者情况、不良反应表现、抗感染药物种类进行评价,并提出针对性预防措施.结果:在本组资料中,女性儿童多于男性,以(1~3)岁和(4~6)岁最为多见;抗菌药物以头孢菌素类、大环内酯类、青霉素类最为常见;不良反应表现最易累及皮肤及其附件、消化系统、呼吸系统.结论:加强儿童抗菌药物使用管理,做好药物不良反应监测工作,减少或避免药物不良反应的发生.
목적:총결아원근3년래인동항감염약물불량반응특정,위림상합리용약제공이론의거.방법:대아원2010년~2012년158례인동응용항균약물인기적불량반응진행분석,종환자정황、불량반응표현、항감염약물충류진행평개,병제출침대성예방조시.결과:재본조자료중,녀성인동다우남성,이(1~3)세화(4~6)세최위다견;항균약물이두포균소류、대배내지류、청매소류최위상견;불량반응표현최역루급피부급기부건、소화계통、호흡계통.결론:가강인동항균약물사용관리,주호약물불량반응감측공작,감소혹피면약물불량반응적발생.
@@@@Objective:To review the children's adverse reactions induced by anti-infection drugs in the past three years in our hospital and provide a theoretical basis for the correct use of anti-infection drugs.Methods:From 2010 to 2012, 158 cases of children's adverse reactions induced by antimicrobial drugs in our hospital were analyzed. Patient's characteristics, ADR's performance and the classification of anti-infection drugs were evaluated and targeted preventive measures were proposed. Results:In this study, we found that girls had higher risk to be suffered by ADR induced by anti-infection drugs than boys. The most frequently ages range were 1 to 3 and 4 to 6 years. The most common antimicrobial agents induced ADR were cephalosporins, macrolides and penicillins. The ADR performances most likely to involve skin and its appendages, digestive system and respiratory system.Conclusion:Strengthen the management to children's use of antimicrobial agents and the monitoring of adverse drug reactions, reduce or avoid the occurrence of adverse drug reactions.