CAJ | 학술논문

目的:分析肇庆地区新生儿先天性甲状腺功能减低症(CH)筛查情况.方法:对肇庆地区196541例新生儿采取荧光酶免疫分析法(FEIA)测定血促甲状腺素(TSH)水平,可疑阳性者召回再次采集血液复查,阳性召回者采集静脉血,采取化学发光法血测定T3、T4、TSH、FT3、FT4.结果:196541例新生儿检出CH患儿126例,发病率1/1560(0.64‰),男性、女性发病率无显著差异性,无统计学意义(p>0.05).接受正规治疗2~3年的患儿,停药30d随访,绝大部分患儿身体、智力发育达到正常水平.结论:做好新生儿疾病筛查工作,提高筛查率与召回复查率,尽早确诊与治疗,使人口素质增强,降低儿童病残率.
목적:분석조경지구신생인선천성갑상선공능감저증(CH)사사정황.방법:대조경지구196541례신생인채취형광매면역분석법(FEIA)측정혈촉갑상선소(TSH)수평,가의양성자소회재차채집혈액복사,양성소회자채집정맥혈,채취화학발광법혈측정T3、T4、TSH、FT3、FT4.결과:196541례신생인검출CH환인126례,발병솔1/1560(0.64‰),남성、녀성발병솔무현저차이성,무통계학의의(p>0.05).접수정규치료2~3년적환인,정약30d수방,절대부분환인신체、지력발육체도정상수평.결론:주호신생인질병사사공작,제고사사솔여소회복사솔,진조학진여치료,사인구소질증강,강저인동병잔솔.
Objectives: To analye the results of neonatal congenital hypothyroidism(CH) in Zhaoqing area.Processes: A total of 196541 cases new-born in Zhaoqing area were deliberately the level of serum thyroid-stimulating hormone (TSH) by using the fluorescent enzyme immunoassay (FEIA).If the (TSH) result assumed musculine gender, then recolect the patient`s venous blood by using the chemiluminescence method to determine the level of T3、T4、TSH、FT3 and FT4.Results: 126 cases of children were confirmed from 196541 cases. The incidence rate have no significant difference between male an female, and the different between male and female is too smal to be statisticaly significance (P>0.05).After two or three years formal treatment to the patient, the vast majority of children`s physical and inteligence were developed into normal level after drug withdrawal for 30 days.Conclusions: We may diagnose and cure as soon as possible by accomplish the neonatal disease screening and improving the early screening and rechecking which can enhance the quality of population and reduce child morbidity.