CAJ | 학술논문

目的探讨氨磺必利治疗慢性精神分裂症的临床疗效.方法回顾性分析我院2011年~2012年间收治的49例慢性精神分裂症患者的临床资料,所有患者均给予氨磺必利治疗,采用阳性与阴性症状量表(PANSS)对临床疗效进行评价,详细记录不良反应情况.结果患者治疗后的PANSS阳性因子和阴性因子较治疗前有显著改善,差异有统计学意义(P<0.05),治疗后痊愈14例,显效21例,有效10例,无效4例,治疗总有效率为91.8%.本组患者治疗后3例患者出现锥体外系不良反应,1例患者出现失眠,1例患者出现头痛,体重、血糖、血脂、及心电图无异常变化.结论采用氨磺必利治疗慢性精神分裂症临床疗效好,安全性高,值得临床进一步推广使用.
목적탐토안광필리치료만성정신분렬증적림상료효.방법회고성분석아원2011년~2012년간수치적49례만성정신분렬증환자적림상자료,소유환자균급여안광필리치료,채용양성여음성증상량표(PANSS)대림상료효진행평개,상세기록불량반응정황.결과환자치료후적PANSS양성인자화음성인자교치료전유현저개선,차이유통계학의의(P<0.05),치료후전유14례,현효21례,유효10례,무효4례,치료총유효솔위91.8%.본조환자치료후3례환자출현추체외계불량반응,1례환자출현실면,1례환자출현두통,체중、혈당、혈지、급심전도무이상변화.결론채용안광필리치료만성정신분렬증림상료효호,안전성고,치득림상진일보추엄사용.
Objective To investigate the clinical effect of amisulpride in treatment of chronic schizophrenia. Methods A retrospective analysis about clinical data of 49 cases of chronic schizophrenia in our hospital from 2011 to 2012 was operated, al patients were given amisulpride treatment, used positive and negative symptom scale (PANSS) to evaluate the clinical effect, recorded the adverse reactions. Results After treatment PANSS positive factors and negative factors of patients were significantly improved than before, the difference was statisticaly significant (P<0.05), 14 cases were cured, effective in 21 cases, valid in 10 cases, invalid 4 cases, the total effective rate was 91.8%. During treatment 3 cases occurred EPS, 1 cases occurred insomnia, 1 patients occurred headache, body weight, blood glucose, blood lipid were no abnormal change. Conclusion Taking amisulpride in treatment of the chronic schizophrenia has good clinical effect, and has high safety, it is worthy of further clinical application.