中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
9期
15-16
,共2页
脆性糖尿病%胰岛素泵%6时段%24时段
脆性糖尿病%胰島素泵%6時段%24時段
취성당뇨병%이도소빙%6시단%24시단
Fragile diabetes mellitus%Continuous subcutaneous insulin infusion (CSII)%6 parts%24 parts
目的比较6段法与24段法两种胰岛素泵基础率输注方式治疗脆性糖尿病的临床疗效及安全性.方法选择20例脆性糖尿病患者,随机分为两组,A组设置6时段基础率,B组设置24时段基础率.两组患者均测血糖谱(每天三餐前、三餐后2h、睡前及凌晨3点血糖).根据血糖结果调整胰岛素用量,直至血糖达标.观察血糖达标时间、每天胰岛素用量及低血糖发生率.结果两组患者治疗后血糖值均能明显下降,差别有统计学意义(P<0.01);两组间治疗前后比较,差别无统计学意义(P>0.05).24时段基础率治疗后血糖达标所用时间短,胰岛素用量少,低血糖发生率低,两组差别有统计学意义(P<0.01).结论24段法胰岛素泵基础率输注模式治疗脆性糖尿病的临床疗效及安全性优于6时段基础率输注.
目的比較6段法與24段法兩種胰島素泵基礎率輸註方式治療脆性糖尿病的臨床療效及安全性.方法選擇20例脆性糖尿病患者,隨機分為兩組,A組設置6時段基礎率,B組設置24時段基礎率.兩組患者均測血糖譜(每天三餐前、三餐後2h、睡前及凌晨3點血糖).根據血糖結果調整胰島素用量,直至血糖達標.觀察血糖達標時間、每天胰島素用量及低血糖髮生率.結果兩組患者治療後血糖值均能明顯下降,差彆有統計學意義(P<0.01);兩組間治療前後比較,差彆無統計學意義(P>0.05).24時段基礎率治療後血糖達標所用時間短,胰島素用量少,低血糖髮生率低,兩組差彆有統計學意義(P<0.01).結論24段法胰島素泵基礎率輸註模式治療脆性糖尿病的臨床療效及安全性優于6時段基礎率輸註.
목적비교6단법여24단법량충이도소빙기출솔수주방식치료취성당뇨병적림상료효급안전성.방법선택20례취성당뇨병환자,수궤분위량조,A조설치6시단기출솔,B조설치24시단기출솔.량조환자균측혈당보(매천삼찬전、삼찬후2h、수전급릉신3점혈당).근거혈당결과조정이도소용량,직지혈당체표.관찰혈당체표시간、매천이도소용량급저혈당발생솔.결과량조환자치료후혈당치균능명현하강,차별유통계학의의(P<0.01);량조간치료전후비교,차별무통계학의의(P>0.05).24시단기출솔치료후혈당체표소용시간단,이도소용량소,저혈당발생솔저,량조차별유통계학의의(P<0.01).결론24단법이도소빙기출솔수주모식치료취성당뇨병적림상료효급안전성우우6시단기출솔수주.
Objective?To discuss the clinical effect of 6 parts continuous subcutaneous insulin infusion (CSII) and 24 parts CSII on patients with fragile diabetes mellitus. Methods Thirty patients with fragile diabetes mellitus were randomly divided into 6 parts CSII group(15 patients) and 24 parts CSII group(15 patients). The levels of plasma glucose, insulin doses, therapeutic time and hypoglucemia were observsed.Result Two CSII groups all could lower blood sugar effectively(P<0.01), and there was no significant differences between two CSII groups(P>0.05).The therapeutic time, insulin doses and hypoglucemia of 24 parts CSII group was superior to 6 parts CSII group(P<0.01, P<0.01, P<0.01). Conclusion The limited evidence shows that 24 parts CSII group is superior to 6 parts CSII group in treating patients with fragile diabetes mellitus