CAJ | 학술논문

目的分析甲状腺功能减退症的临床特征、病因及主要误诊原因.方法对46例甲状腺功能减退症患者的临床资料进行回顾性分析.结果在46例甲状腺功能减退症患者中,女38例(82.60%)、男8例(17.40%)、男∶女=1∶4.75;40岁以上30例(65.21%);原发性甲状腺功能减退症43例(93.48%)、中枢性甲状腺功能减退症3例(6.52%);其中,在原发性甲减中,甲亢服放射性核素131I后20例(46.51%)、乔本氏甲状腺炎10例(23.26%)、甲亢药物治疗后4例(9.30%)、甲亢手术治疗后3例(6.98%)、其他尙有甲状腺癌手术后、颈部放疗后等,均较少见.有21例误诊为其他疾病,误诊率(45.65%).结论甲状腺功能减退症好发于40岁以上的中老年人,尤以女性多见.发病原因繁多复杂,临床表现不典型,极易造成误诊或漏诊,应引起高度重视.
목적분석갑상선공능감퇴증적림상특정、병인급주요오진원인.방법대46례갑상선공능감퇴증환자적림상자료진행회고성분석.결과재46례갑상선공능감퇴증환자중,녀38례(82.60%)、남8례(17.40%)、남∶녀=1∶4.75;40세이상30례(65.21%);원발성갑상선공능감퇴증43례(93.48%)、중추성갑상선공능감퇴증3례(6.52%);기중,재원발성갑감중,갑항복방사성핵소131I후20례(46.51%)、교본씨갑상선염10례(23.26%)、갑항약물치료후4례(9.30%)、갑항수술치료후3례(6.98%)、기타상유갑상선암수술후、경부방료후등,균교소견.유21례오진위기타질병,오진솔(45.65%).결론갑상선공능감퇴증호발우40세이상적중노년인,우이녀성다견.발병원인번다복잡,림상표현불전형,겁역조성오진혹루진,응인기고도중시.
Objective?To analyze clinical features and etiology of primary hypothyroidism and main causes of misdiagnosis. Method Forty-six cases of primary hypothyroidism were reviewed. Results Of the 46 cases of primary hypothyroidism,38 cases were female(82.60%),8 cases were male(17.40%),the proportion of male and female is 1∶4.75.30 cases are above 30 years old(65.21%). 43 cases were primary hypothyroidism(93.48%).3 cases were central primary hypothyroidism. Of all the primary hypothyroidism cases, 20 cases were hyperthyroidism with radionuclide131cure(46.51%),4 cases were chronic thyroiditis(23.26%),4 cases were treated with hyperthyroid drugs(9.30%),3 cases were with surgical treatment of hyperthyroidism(6.98%).The other cases with treatment of thyroid carcinoma surgery or neck radiotherapy were rare.21 cases (45.65%) were misdiagnosed. Conclusion Primary hypothyroidism are more likely to afflict people above 40,especially the females. The causes of disease are complex, and the clinical manifestation is not typical, which easily result to misdiagnosis. More attention should be paid to this.