CAJ | 학술논문

直接测量颈椎管容积和颈脊髓体积可以较全面、立体地反映颈椎管对颈段脊髓的包容情况,尸体标本石蜡灌注法、树脂灌注法和有限元模型法均具参考价值,但操作繁复,且较难应用于临床,目前尚缺乏能够准确测量颈脊髓体积和颈椎管容积的简便测量方法.:探讨颈椎管容积与颈脊髓体积比值与脊髓型颈椎病(CSM)临床症状的相关性.:根据JOA评分将CSM患者分为A组(轻度)31例及B组(中重度)27例,所有患者均接受颈椎MRI扫描并计算颈椎管容积与颈脊髓体积比值,对两组患者的颈椎管容积与颈脊髓体积比值进行独立样本t检验,对两组患者的颈椎管容积与颈脊髓体积比值和JOA评分进行相关性分析.:A组患者的颈椎管容积与颈脊髓体积比值明显大于B组(t=15.094, P=0.001);B组患者的颈椎管容积与颈脊髓体积比值与JOA评分的决定系数(r2=0.738)高于A组(r2=0.563);颈椎管容积与颈脊髓体积比值与JOA评分的线性回归趋势提示A、B两组患者的颈椎管容积与颈脊髓体积比值均与JOA评分呈正相关.:颈椎管容积与颈脊髓体积比值可以反映颈椎管对颈脊髓的包容状态,利用MRI测量颈椎管容积与颈脊髓体积比值可以定量反映脊髓的损害程度.目的方法结果结论
직접측량경추관용적화경척수체적가이교전면、입체지반영경추관대경단척수적포용정황,시체표본석사관주법、수지관주법화유한원모형법균구삼고개치,단조작번복,차교난응용우림상,목전상결핍능구준학측량경척수체적화경추관용적적간편측량방법.:탐토경추관용적여경척수체적비치여척수형경추병(CSM)림상증상적상관성.:근거JOA평분장CSM환자분위A조(경도)31례급B조(중중도)27례,소유환자균접수경추MRI소묘병계산경추관용적여경척수체적비치,대량조환자적경추관용적여경척수체적비치진행독립양본t검험,대량조환자적경추관용적여경척수체적비치화JOA평분진행상관성분석.:A조환자적경추관용적여경척수체적비치명현대우B조(t=15.094, P=0.001);B조환자적경추관용적여경척수체적비치여JOA평분적결정계수(r2=0.738)고우A조(r2=0.563);경추관용적여경척수체적비치여JOA평분적선성회귀추세제시A、B량조환자적경추관용적여경척수체적비치균여JOA평분정정상관.:경추관용적여경척수체적비치가이반영경추관대경척수적포용상태,이용MRI측량경추관용적여경척수체적비치가이정량반영척수적손해정도.목적방법결과결론
@@@@Background:Measuring the volume of the cervical spinal canal and the cervical spinal cord directly can comprehensively and vividly reflect the inclusive status of the cervical spinal canal to the cervical spinal cord. The methods of paraffin perfu-sion in the cadaver, resin infusion and finite element model, though have reference value, are very complicated and difficult to apply in clinic. Therefore, there still lack some easy ways to accurately measure the volume of cervical spinal cord and cervical spinal canal. Objective:To investigate the relationship between the severity of cervical spondylotic myelopathy (CSM) and the ratio of the cervical spinal canal volume to the cervical spinal cord volume. Methods:Divide the patients with CSM into 2 groups according to the Japanese Orthopaedic Association (JOA) scores. Group A (mild) has 31 patients and group B (moderate to severe) has 27 patients. Perform the MRI (Magnetic Resonance Imaging) scan on each patient and calculate the ratios of the cervical spinal canal volume to the cervical spinal cord volume. Conduct in-dependent-sample T test on each ratio of the 2 groups. And analyze the correlation between the ratios and the JOA scores. Results:Ratios of the cervical spinal canal volume to the cervical spinal cord volume of group A are significantly higher than that ratios of group B (t=15.094, P=0.001);While the coefficient of determination of that ratios of group B and JOA scores (r2=0.738) is higher than that of group A (r2=0.563);The linear regression trend of the ratio of the cervical spinal canal vol-ume to the cervical spinal cord volume and the JOA scores shows that this ratio has positive correlation with JOA scores. Conclusions:The ratio of the cervical spinal canal volume to the cervical spinal cord volume can reflect the inclusive status of the cervical spinal canal to the cervical spinal cord. Adopting MRI in measuring this ratio can quantitatively reflect the damage extent of the spinal cord.