中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
11期
434-435
,共2页
ICU%机械通气%咪唑安定%芬太尼
ICU%機械通氣%咪唑安定%芬太尼
ICU%궤계통기%미서안정%분태니
ICU%Mechanical ventilation%Imidazole stability%Fentanyl
目的观察ICU危重患者机械通气中咪唑安定与芬太尼的临床镇静作用及效果.方法对我院59例ICU收治的危重需行机械通气的患者进行镇静药物的分组临床观察,29例患者在机械通气中使用芬太尼,30例患者在机械通气中使用咪唑安定.观察两组患者用药后的起效时间以及神志恢复时间,并观察两组患者呼吸以及血氧饱和度(SaO2)、动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)等指标.结果芬太尼均让患者达到Ramsay氏分级标准3~4级的时间明显短于咪唑安定,而平均药物起效时间以及术后神志恢复时间,芬太尼组亦明显短于咪唑安定组.另外,两组患者呼吸以及SaO2、PaO2、PaCO2等指标上均较使用前有明显的改善(P<0.01),组间进行比较并无统计学意义(P>0.05).结论 ICU危重患者机械通气中使用咪唑安定或芬太尼均有较好的镇静作用,临床可根据具体情况进行选择.
目的觀察ICU危重患者機械通氣中咪唑安定與芬太尼的臨床鎮靜作用及效果.方法對我院59例ICU收治的危重需行機械通氣的患者進行鎮靜藥物的分組臨床觀察,29例患者在機械通氣中使用芬太尼,30例患者在機械通氣中使用咪唑安定.觀察兩組患者用藥後的起效時間以及神誌恢複時間,併觀察兩組患者呼吸以及血氧飽和度(SaO2)、動脈血氧分壓(PaO2)、動脈血二氧化碳分壓(PaCO2)等指標.結果芬太尼均讓患者達到Ramsay氏分級標準3~4級的時間明顯短于咪唑安定,而平均藥物起效時間以及術後神誌恢複時間,芬太尼組亦明顯短于咪唑安定組.另外,兩組患者呼吸以及SaO2、PaO2、PaCO2等指標上均較使用前有明顯的改善(P<0.01),組間進行比較併無統計學意義(P>0.05).結論 ICU危重患者機械通氣中使用咪唑安定或芬太尼均有較好的鎮靜作用,臨床可根據具體情況進行選擇.
목적관찰ICU위중환자궤계통기중미서안정여분태니적림상진정작용급효과.방법대아원59례ICU수치적위중수행궤계통기적환자진행진정약물적분조림상관찰,29례환자재궤계통기중사용분태니,30례환자재궤계통기중사용미서안정.관찰량조환자용약후적기효시간이급신지회복시간,병관찰량조환자호흡이급혈양포화도(SaO2)、동맥혈양분압(PaO2)、동맥혈이양화탄분압(PaCO2)등지표.결과분태니균양환자체도Ramsay씨분급표준3~4급적시간명현단우미서안정,이평균약물기효시간이급술후신지회복시간,분태니조역명현단우미서안정조.령외,량조환자호흡이급SaO2、PaO2、PaCO2등지표상균교사용전유명현적개선(P<0.01),조간진행비교병무통계학의의(P>0.05).결론 ICU위중환자궤계통기중사용미서안정혹분태니균유교호적진정작용,림상가근거구체정황진행선택.
Objective To observe the critically ill patients in ICU mechanical ventilation imidazole stability and fentanyl clinical sedation and effect. Methods Clinical data of 59 cases of ICU patients need to do of critically ill patients with mechanical ventilation calm drug clinical observation group, 29 patients with mechanical ventilation in the use of fentanyl, 30 patients with mechanical ventilation in use imidazole stability. The two groups were observed after the onset time and mind recovery time, and observe the two groups were breathing and blood oxygen saturation (SaO2), arterial blood oxygen partial pressure (PaO2), arterial blood carbon dioxide partial pressure (PaCO2), and other indicators. Results Fentanyl are let patients achieve Ramsay's classifcation standard grade 3-4 time significantly shorter than imidazole stability, and the average drugs work time and postoperative recovery time consciousness, fentanyl group also signifcantly shorter than imidazole group stability. In addition, two groups of patients breathe and SaO2, PaO2, PaCO2 and indicator than before use has improved remarkably (P<0.01), the comparison between groups and no statistical signifcance (P>0.05). Conclusion ICU critically ill patients with mechanical ventilation in using imidazole stability or fentanyl are better sedation, clinical can choose according to the specifc circumstances.