CAJ | 학술논문

目的:观察归脾汤小肠内滴注对腹腔镜胃癌根治术后疲劳综合征的改善作用.方法:39例胃癌患者术前随机分为对照组19例,观察组20例,两组术后均给予等氮、等热量肠内营养支持.观察组同时给予肠内滴注归脾汤100mL,1天1次,共7天.观察两组术后一般情况,分别应用视觉模拟疲劳尺、心境量表评估手术前后患者疲劳程度、心境变化.于术后第2、8天检测血清蛋白水平(总蛋白、白蛋白、前白蛋白)、T淋巴细胞亚群(CD4+、CD8+、CD4+/CD8+).结果:腹腔镜胃癌手术后中药小肠内滴注未增加术后并发症,观察组心境状态好于对照组(P<0.05),术后疲劳程度较对照组减轻明显(P<0.05);术后8天观察组血清前白蛋白、白蛋白、CD4+、CD4+/CD8+等观察指标均比对照组增高(P<0.05).结论:胃癌患者腹腔镜手术后早期行肠内营养联合中药滴注安全有效,能明显改善机体的营养状态和术后疲劳综合征.
목적:관찰귀비탕소장내적주대복강경위암근치술후피로종합정적개선작용.방법:39례위암환자술전수궤분위대조조19례,관찰조20례,량조술후균급여등담、등열량장내영양지지.관찰조동시급여장내적주귀비탕100mL,1천1차,공7천.관찰량조술후일반정황,분별응용시각모의피로척、심경량표평고수술전후환자피로정도、심경변화.우술후제2、8천검측혈청단백수평(총단백、백단백、전백단백)、T림파세포아군(CD4+、CD8+、CD4+/CD8+).결과:복강경위암수술후중약소장내적주미증가술후병발증,관찰조심경상태호우대조조(P<0.05),술후피로정도교대조조감경명현(P<0.05);술후8천관찰조혈청전백단백、백단백、CD4+、CD4+/CD8+등관찰지표균비대조조증고(P<0.05).결론:위암환자복강경수술후조기행장내영양연합중약적주안전유효,능명현개선궤체적영양상태화술후피로종합정.
Objective: To observe the therapeutic effect of Guipi decoction on the treatment of postoperative fa?tigue syndrome in patients received laparoscopy-assisted radical gastrectomy for gastric cancer. Methods: A total of 39 patients with gastric cancer were randomly divided into control group(n=19) and medicine group(n=20). Both groups received the same enteral nutrition support after operation. The medicine group received extra Guipi decoction given at the dose of 100 ml through small bowel drip once a day for 7 days. General performance was observed in both groups. Visual analogue scales and profile of mood states were used to compare. Serum lev?els of total protein, albumin, and prealbumin, and T cell subpopulations(CD4+, CD8+, CD4+/CD8+) were deter?mined on day 2 and 8 after operation. Results: Extra Guipi decoction did not increase the incidence of compli?cations of radical gastrectomy for gastric cancer. Patients received Guipi decoction had better performance in visu?al analogue scales and profile of mood state test(both P<0.05). Except the serum level of total protein, other in?dex were all higher in the medicine group as compared to those in the control group(P<0.05). Conclusion: En?teral nutrition combined with Guipi drip at the early stage after operation can improve the nutritional status and attenuate the postoperative fatigue syndrome in patients received laparoscopy-assisted radical gastrectomy for gas?tric cancer.