CAJ | 학술논문

目的:探讨妊娠妇女血清25-羟维生素D水平与妊娠期细菌性阴道病(BV)发生率的关系.方法:对2011-2012年来笔者所在医院进行产检的妊娠期10~12周及24~28周的孕妇各400例进行血清25-(OH)D检测,并取阴道分泌物进行BV检查,对其相关性进行分析.结果:笔者所在地区孕10~12周孕早期妇女25-(OH)D缺乏(≤50.0 nmol/L)的发生率为52.3%,25-(OH)D不足(50.0 nmol/L<25(OH)D≤75.0 nmol/L)的发生率为30.5%,25-(OH)D正常者(>75.0 nmol/L)占17.3%,其相对应的BV的发生率分别为32.1%、23.8%、5.8%.妊娠24~28周孕晚期妇女25-(OH)D缺乏的发生率为61.8%,25-(OH)D不足的发生率为32.8%,25-(OH)D正常者占5.5%,其相对应的BV的发生率分别为40.9%、32.1%、9.1%.对两组进行比较,妊娠24~28周孕妇25-(OH)D异常高于孕10~12周,维生素D下降明显,相对应出现BV感染率显著高.25-(OH)D不足和缺乏的孕妇中BV发生率高于25-(OH)D正常的孕妇(P<0.05).结论:妊娠期细菌性阴道病的发生率与25-羟维生素D缺乏密切相关.
목적:탐토임신부녀혈청25-간유생소D수평여임신기세균성음도병(BV)발생솔적관계.방법:대2011-2012년래필자소재의원진행산검적임신기10~12주급24~28주적잉부각400례진행혈청25-(OH)D검측,병취음도분비물진행BV검사,대기상관성진행분석.결과:필자소재지구잉10~12주잉조기부녀25-(OH)D결핍(≤50.0 nmol/L)적발생솔위52.3%,25-(OH)D불족(50.0 nmol/L<25(OH)D≤75.0 nmol/L)적발생솔위30.5%,25-(OH)D정상자(>75.0 nmol/L)점17.3%,기상대응적BV적발생솔분별위32.1%、23.8%、5.8%.임신24~28주잉만기부녀25-(OH)D결핍적발생솔위61.8%,25-(OH)D불족적발생솔위32.8%,25-(OH)D정상자점5.5%,기상대응적BV적발생솔분별위40.9%、32.1%、9.1%.대량조진행비교,임신24~28주잉부25-(OH)D이상고우잉10~12주,유생소D하강명현,상대응출현BV감염솔현저고.25-(OH)D불족화결핍적잉부중BV발생솔고우25-(OH)D정상적잉부(P<0.05).결론:임신기세균성음도병적발생솔여25-간유생소D결핍밀절상관.
Objective:To discuss the relationship between the level of pregnant women’s serum 25-(OH)D and the incidence rate of pregnancy bacterial vaginal disease (BV).Methods:All the 400 cases of the pregnant women for the gestation period in 10-12 and 24-28 weeks from 2011 to 2012 in our hospital were selected.All the pregnant women were examined the test of the serum 25-(OH)D and the BV inspection.To analyse the correlation between the test of the serum 25-(OH)D and the BV inspection.Results:In local region,the incidence rate was 52.3%when 25-(OH)D was deficiency(≤50.0 nmol/L) for 10-12 weeks early pregnant women,30.5%when it was shortage(50.0 nmol/L<25-(OH)D≤75.0 nmol/L) and 17.3%was normal(>75.0 nmol/L),which relevant incidence rate of BV was 32.1%,23.8%and 5.9%.On the other hand,the incidence rate was 61.8%when 25-(OH)D was deficiency for 24-28 weeks late pregnant women,32.8%when it was shortage and 5.5%was normal,which relevant incidence rate of BV was 40.9%,32.1%and 9.1%.The 25-(OH)D in 24-28 weeks of pregnancy appear obvious anomaly more than 10-12 weeks pregnant women,Vitamin D down significantly,BV infection rate increased significantly.BV incidence in 25-(OH)D deficiency and lack were patency higher than the 25-(OH)D normal(P<0.05).Conclusion:The incidence rate of pregnancy bacterial vaginal disease is closely related to the deficiency of Vitamin D in pregnant women.