CAJ | 학술논문

目的:探讨子宫切除同时切除输卵管对绝经前妇女卵巢功能的近期影响.方法:分析2011年8月-2012年4月在潍坊医学院附属医院行子宫全切+双侧输卵管切除术的10例绝经前患者(试验组)的临床资料,评估手术对卵巢功能的近期影响,并以同期仅采用子宫全切术的10例绝经前患者(试验对照组)及同期10例正常绝经前妇女(空白对照组)做对比.结果:试验组与试验对照组患者术后1个月血FSH、LH、E2较术前均有变化,差异有统计学意义(P<0.05);两组患者术后2、4、6个月血FSH、LH、E2较术前均无明显变化,差异无统计学意义(P>0.05);两组患者术前及术后血FSH、LH、E2组间相比,与首次测量比较差异无统计学意义(P>0.05);空白对照组7个月内血FSH、LH、E2无明显变化,差异无统计学意义(P>0.05).结论:子宫切除可引起绝经前妇女短暂性卵巢功能下降,于术后近期内可逐步恢复;同时切除输卵管并不会加重子宫全切术对绝经前妇女卵巢功能的影响.
목적:탐토자궁절제동시절제수란관대절경전부녀란소공능적근기영향.방법:분석2011년8월-2012년4월재유방의학원부속의원행자궁전절+쌍측수란관절제술적10례절경전환자(시험조)적림상자료,평고수술대란소공능적근기영향,병이동기부채용자궁전절술적10례절경전환자(시험대조조)급동기10례정상절경전부녀(공백대조조)주대비.결과:시험조여시험대조조환자술후1개월혈FSH、LH、E2교술전균유변화,차이유통계학의의(P<0.05);량조환자술후2、4、6개월혈FSH、LH、E2교술전균무명현변화,차이무통계학의의(P>0.05);량조환자술전급술후혈FSH、LH、E2조간상비,여수차측량비교차이무통계학의의(P>0.05);공백대조조7개월내혈FSH、LH、E2무명현변화,차이무통계학의의(P>0.05).결론:자궁절제가인기절경전부녀단잠성란소공능하강,우술후근기내가축보회복;동시절제수란관병불회가중자궁전절술대절경전부녀란소공능적영향.
Objective:To investigate the recent effects of hysterectomy and salpingectomy on ovarian function in premenopausal women.Methods:Choose 30 premenopausal women,10 of them received hysterectomy and salpingectomy (test group),10 of them received hysterectomy (test control group),and 10 of them didn’t receive any treatment (normal control group).The baseline levels of serum E2,FSH,LH among the three groups were compared.Results:In test group and test control group,the baseline endocrine levels changed(E2 decreased;FSH,LH increased) 1 month after operation(P<0.05),but no significant differences in the baseline endocrine levels were found among preoperation and 2,4,6 months after operation(P>0.05).There were no significant differences in the baseline endocrine levels of the same period between test group and test control group(P>0.05).In normal control group,there were no significant differences in the baseline endocrine levels during 7 months(P>0.05).Conclusion:Among the premenopausal women,hysterectomy can cause a transient reduce of ovarian function, which will recover later.And salpingectomy can not exacerbate the effects of hysterectomy on ovarian function.