CAJ | 학술논문

目的针对患有尖锐湿疣的患者进行HPV基因分型并分析,便于疾病的防治与诊断.方法选择2013年1月-2014年1月在湖北省文理学院附属襄阳市中心医院接受检查治疗的90例外阴尖锐湿疣女性患者,避开患者的月经期,使用消毒棉签擦拭宫颈处的分泌物,并使用呈箭形的取样刷在宫颈入口2cm处轻轻旋转若干圈,在疣体上刮取上皮细胞并送检,依据试剂盒说明严格进行操作.结果 90例患者中,有72例检出HPV DNA的基因分型,其检测率为80.0％,其中的高危型发病概率为75.0％(54/72),低危型检出概率43.1％(31/72).单一型感染的患者63例,多重感染者27例.结论外阴尖锐湿疣患者为高危型HPV高感染率人群,在对症治疗的同时更应重视高危型HPV的检测.
목적 침대환유첨예습우적환자진행HPV기인분형병분석,편우질병적방치여진단.방법 선택2013년1월-2014년1월재호북성문이학원부속양양시중심의원접수검사치료적90예외음첨예습우녀성환자,피개환자적월경기,사용소독면첨찰식궁경처적분비물,병사용정전형적취양쇄재궁경입구2cm처경경선전약간권,재우체상괄취상피세포병송검,의거시제합설명엄격진행조작.결과 90례환자중,유72례검출HPV DNA적기인분형,기검측솔위80.0％,기중적고위형발병개솔위75.0％(54/72),저위형검출개솔43.1％(31/72).단일형감염적환자63례,다중감염자27례.결론 외음첨예습우환자위고위형HPV고감염솔인군,재대증치료적동시경응중시고위형HPV적검측.
Objective HPV genotyping of condyloma acuminatum patients was tested and analyzed for the prevention and diagnosis of diseases.Methods 90 cases of vulvar condyloma acuminatum female patients in the Affiliated Central Hospital of Hubei University of Art and Science from January 2013 to January 2014 were collected as research subjects.Swab samples was collected and tested according to the manual operation.Results For these 90 patients,72 cases were detected HPV gene typing for DNA.The detection rate was 80％,the incidence of high-risk types in which was 75％ (54/72) and low risk type detection probability was 43.1％ (31/72).63 cases were single type infection and 27 cases were multiple infection.Conclusions There is high risk of HPV high infection rate for vulva condyloma acuminatum patients and more attention should be paid to the detection of high-risk HPV in symptomatic.