中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
11期
1172-1175
,共4页
陈洪滔%黄浩桂%朱丹%万启军%何永成
陳洪滔%黃浩桂%硃丹%萬啟軍%何永成
진홍도%황호계%주단%만계군%하영성
腹膜透析%左心室肥厚%腹膜转运特性%超声心动图
腹膜透析%左心室肥厚%腹膜轉運特性%超聲心動圖
복막투석%좌심실비후%복막전운특성%초성심동도
Peritoneal Dialysis%Left ventricular hypertrophy%Transport property%Echocardiography
目的 探讨腹膜透析患者左心室肥厚与腹膜转运特性的关系.方法 69例持续性不卧床腹膜透析(CAPD)患者,超声心动图检查测算左心室心肌质量指数(LVMI),应用改良腹膜平衡试验(PET),按患者腹膜转运类型分高转运组、高平均转运组、低平均转运组及低转运组,同时检测血红蛋白、血白蛋白、尿素氮、肌酐等,以及测定尿素清除指数(Kt/V)和肌酐清除率(Ccr),记录透析龄、收缩压、舒张压.结果 腹膜高转运和高平均转运例数比低转运和低平均转运多(41/28);高转运组、高平均转运组、低平均转运组、低转运组透析龄分别为(39.2±21.8)、(26.6±15.6)、(28.6±14.4)、(45.7±35.0)岁,4组间差异有统计学意义(F=4.128,P＜0.05),高转运组透析龄比高平均转运组、低平均转运组长(P均＜0.05),低转运组透析龄比高平均转运组、低平均转运组长(P均＜0.05);LVMI与4h透析液肌酐与血肌酐比值(D/Pcr)、收缩压、舒张压呈正相关(r值分别为0.339、0.351、0.316,P均＜0.01),与白蛋白呈负相关(r=-0.292,P＜0.05);69例CAPD患者发生左心室肥厚44例,发生率63.8％,高转运组高于低平均转运组及低转运组(x2值分别为5.455、5.091,P均＜0.05).结论 维持性腹膜透析患者高转运特性占大多数,有较高左心室肥厚发生率,高转运者更为明显.D/Pcr、收缩压、舒张压升高和低白蛋白与左心室肥厚密切相关.
目的 探討腹膜透析患者左心室肥厚與腹膜轉運特性的關繫.方法 69例持續性不臥床腹膜透析(CAPD)患者,超聲心動圖檢查測算左心室心肌質量指數(LVMI),應用改良腹膜平衡試驗(PET),按患者腹膜轉運類型分高轉運組、高平均轉運組、低平均轉運組及低轉運組,同時檢測血紅蛋白、血白蛋白、尿素氮、肌酐等,以及測定尿素清除指數(Kt/V)和肌酐清除率(Ccr),記錄透析齡、收縮壓、舒張壓.結果 腹膜高轉運和高平均轉運例數比低轉運和低平均轉運多(41/28);高轉運組、高平均轉運組、低平均轉運組、低轉運組透析齡分彆為(39.2±21.8)、(26.6±15.6)、(28.6±14.4)、(45.7±35.0)歲,4組間差異有統計學意義(F=4.128,P＜0.05),高轉運組透析齡比高平均轉運組、低平均轉運組長(P均＜0.05),低轉運組透析齡比高平均轉運組、低平均轉運組長(P均＜0.05);LVMI與4h透析液肌酐與血肌酐比值(D/Pcr)、收縮壓、舒張壓呈正相關(r值分彆為0.339、0.351、0.316,P均＜0.01),與白蛋白呈負相關(r=-0.292,P＜0.05);69例CAPD患者髮生左心室肥厚44例,髮生率63.8％,高轉運組高于低平均轉運組及低轉運組(x2值分彆為5.455、5.091,P均＜0.05).結論 維持性腹膜透析患者高轉運特性佔大多數,有較高左心室肥厚髮生率,高轉運者更為明顯.D/Pcr、收縮壓、舒張壓升高和低白蛋白與左心室肥厚密切相關.
목적 탐토복막투석환자좌심실비후여복막전운특성적관계.방법 69례지속성불와상복막투석(CAPD)환자,초성심동도검사측산좌심실심기질량지수(LVMI),응용개량복막평형시험(PET),안환자복막전운류형분고전운조、고평균전운조、저평균전운조급저전운조,동시검측혈홍단백、혈백단백、뇨소담、기항등,이급측정뇨소청제지수(Kt/V)화기항청제솔(Ccr),기록투석령、수축압、서장압.결과 복막고전운화고평균전운례수비저전운화저평균전운다(41/28);고전운조、고평균전운조、저평균전운조、저전운조투석령분별위(39.2±21.8)、(26.6±15.6)、(28.6±14.4)、(45.7±35.0)세,4조간차이유통계학의의(F=4.128,P＜0.05),고전운조투석령비고평균전운조、저평균전운조장(P균＜0.05),저전운조투석령비고평균전운조、저평균전운조장(P균＜0.05);LVMI여4h투석액기항여혈기항비치(D/Pcr)、수축압、서장압정정상관(r치분별위0.339、0.351、0.316,P균＜0.01),여백단백정부상관(r=-0.292,P＜0.05);69례CAPD환자발생좌심실비후44례,발생솔63.8％,고전운조고우저평균전운조급저전운조(x2치분별위5.455、5.091,P균＜0.05).결론 유지성복막투석환자고전운특성점대다수,유교고좌심실비후발생솔,고전운자경위명현.D/Pcr、수축압、서장압승고화저백단백여좌심실비후밀절상관.
Objective To investigate the association between left ventricular hypertrophy and peritoneal transport properties in Peritoneal Dialysis patients.Methods Sixty-nine Continuous Ambulatory Peritoneal Dialysis (CAPD)patients were enrolled in current study.All patients underwent echocardiography for left ventricular mass index (LVMI).Transport status was categorized as high transport,high average transport,low average transport and low transport based on modified peritoneal equilibration test (PET).The data collected included hemoglobin,albumin,blood urea nitrogen,creatinine,urea clearance (Kt/V) and creatinine clearance rate (Ccr),dialysis vintage,systolic blood pressure,diastolic blood pressure.Results Patients with high transport status were 41 cases,more than those with low transport status(28 cases).The dialysis age of high transport,high average transport,low average transport and low transport vintage were (39.2 ± 21.8),(26.6 ±15.6),(28.6 ± 14.4),(45.7 ± 35.0) years old respectively,and the difference was significant (F =4.128,P ＜ 0.05).The dialysis age in the higher transport group was longer than that in high average transport group and low average transport group (P ＜ 0.05).LVMI has significant positive correlations with D/Pcr at 4th hour,SBP and DBP (r =0.339,0.351,0.316,P ＜ 0.01) and the negative correlation with albmin (r =-0.292,P ＜0.05).Left ventricular hypertrophy(LVH) in all patients was 63.8％,ant it was higher in high transport group than that low average transport and low transport group (x2 =5.455,5.091,P ＜ 0.05) Conclusion High transport status is the most common in CAPD patients.There is high incident rate of LVH in this population.LVH has significant positive correlations with D/Pcr,higher SBP,DBP,and lower albumin.
