海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
24期
3649-3651,3652
,共4页
耳鼻喉手术%曲马多%氟哌利多%镇痛
耳鼻喉手術%麯馬多%氟哌利多%鎮痛
이비후수술%곡마다%불고리다%진통
ENT surgery%Tramadol%Droperidol%Anesthesia
目的：探讨曲马多联合氟哌利多应用于耳鼻喉手术的镇痛效果及安全性。方法选取2012年4月至2013年4月在我院接受耳鼻喉手术的70例患者为研究对象，随机分为观察组36例与对照组34例，观察组应用曲马多联合氟哌利多治疗，于手术开始局麻前静脉注射曲马多3 mg/kg和氟哌利多0.04 mg/kg，并使用微量泵持续输注二者的混合液约24h；对照组患者使用利多卡因进行常规的局部麻醉。观察记录两组患者术后1h、4h、8h、12h的疼痛视觉模拟评分(VAS)分值，麻醉剂注入前（T0)、注入后(T1)、手术开始(T2)、手术结束(T3)的血流动力学变化及不良反应。结果观察组患者疼痛程度在术后1h、4h、8h的VAS评分明显低于对照组，差异有显著统计学意义(P<0.01)，术后12 h与对照组比较差异无统计学意义(P>0.05)；对照组患者的SBP、DBP、HR指标比观察组波动幅度大，观察组的麻醉效果比对照组稳定；观察组术后不良反应的总发生率(8.33%)也明显低于对照组(23.53%)， P<0.05。结论曲马多联合氟哌利多应用于耳、鼻、喉手术的镇痛效果好，能有效提高患者生活质量，值得临床推广使用。
目的：探討麯馬多聯閤氟哌利多應用于耳鼻喉手術的鎮痛效果及安全性。方法選取2012年4月至2013年4月在我院接受耳鼻喉手術的70例患者為研究對象，隨機分為觀察組36例與對照組34例，觀察組應用麯馬多聯閤氟哌利多治療，于手術開始跼痳前靜脈註射麯馬多3 mg/kg和氟哌利多0.04 mg/kg，併使用微量泵持續輸註二者的混閤液約24h；對照組患者使用利多卡因進行常規的跼部痳醉。觀察記錄兩組患者術後1h、4h、8h、12h的疼痛視覺模擬評分(VAS)分值，痳醉劑註入前（T0)、註入後(T1)、手術開始(T2)、手術結束(T3)的血流動力學變化及不良反應。結果觀察組患者疼痛程度在術後1h、4h、8h的VAS評分明顯低于對照組，差異有顯著統計學意義(P<0.01)，術後12 h與對照組比較差異無統計學意義(P>0.05)；對照組患者的SBP、DBP、HR指標比觀察組波動幅度大，觀察組的痳醉效果比對照組穩定；觀察組術後不良反應的總髮生率(8.33%)也明顯低于對照組(23.53%)， P<0.05。結論麯馬多聯閤氟哌利多應用于耳、鼻、喉手術的鎮痛效果好，能有效提高患者生活質量，值得臨床推廣使用。
목적：탐토곡마다연합불고리다응용우이비후수술적진통효과급안전성。방법선취2012년4월지2013년4월재아원접수이비후수술적70례환자위연구대상，수궤분위관찰조36례여대조조34례，관찰조응용곡마다연합불고리다치료，우수술개시국마전정맥주사곡마다3 mg/kg화불고리다0.04 mg/kg，병사용미량빙지속수주이자적혼합액약24h；대조조환자사용리다잡인진행상규적국부마취。관찰기록량조환자술후1h、4h、8h、12h적동통시각모의평분(VAS)분치，마취제주입전（T0)、주입후(T1)、수술개시(T2)、수술결속(T3)적혈류동역학변화급불량반응。결과관찰조환자동통정도재술후1h、4h、8h적VAS평분명현저우대조조，차이유현저통계학의의(P<0.01)，술후12 h여대조조비교차이무통계학의의(P>0.05)；대조조환자적SBP、DBP、HR지표비관찰조파동폭도대，관찰조적마취효과비대조조은정；관찰조술후불량반응적총발생솔(8.33%)야명현저우대조조(23.53%)， P<0.05。결론곡마다연합불고리다응용우이、비、후수술적진통효과호，능유효제고환자생활질량，치득림상추엄사용。
Objective To investigate the analgesic effect and safety of tramadol combining droperidol in ENT surgery. Methods Seventy patients accepted ENT surgery were divided into observation group (36 cases) and control group (34 cases) randomly. The former were treated with tramadol (3 mg/kg) combined with droperidol (0.04 mg/kg) five minutes before starting ENT surgery, and the latter received conventional local anesthesia. Pain visu-al analogue scale (VAS) scores 1 h, 4 h, 8 h, 12 h after surgery, hemodynamic changes and adverse reactions before an-esthesia (T0), after anesthesia (T1), at the beginning of surgery (T2), at the end of surgery (T3) were observed and statisti-cally analyzed. Results Compared with control group, the VAS scores 1 h, 4 h, 8 h after surgery of observation group were significantly lower (P<0.01), with no statistically significant difference 12 h after surgery (P>0.05). Chang-es in SBP, DBP, HR of the control group were larger, and the anesthetic effect of the observation group was more sta-ble. The incidence of adverse reactions after ENT surgery of observation group (8.33%) were significantly lower than 23.53%of the control group (P<0.05). Conclusion Tramadol combined with droperidol has significant analgesic ef-fect for ENT surgery and can improve the life quality of patients effectively.
