中国现代药物应用
中國現代藥物應用
중국현대약물응용
CHINESE JOURNAL OF MODERN DRUG APPLICATION
2015年
2期
14-15
,共2页
右美托咪定%七氟醚%麻醉恢复期%精神运动性激动
右美託咪定%七氟醚%痳醉恢複期%精神運動性激動
우미탁미정%칠불미%마취회복기%정신운동성격동
Dexmedetomidine%Sevoflurane%Anesthesia recovery period%Psychomotor agitation
目的：观察右美托咪定对七氟醚复合麻醉斜视矫正术患儿苏醒期躁动的影响。方法40例择期拟行斜视矫正术的患儿,采用随机数字表法分成两组：生理盐水对照组(Ⅰ组, n=20)和右美托咪定组(Ⅱ组, n=20)。静脉注射芬太尼2μg/kg,异丙酚3 mg/kg完成诱导插入喉罩,术中吸入2%~3.5%七氟醚维持麻醉。插入喉罩即刻Ⅱ组输注右美托咪定0.2μg/(kg·h),Ⅰ组输注等剂量的生理盐水。手术结束时停止输注右美托咪定和生理盐水。记录两组手术时间、拔管时间、麻醉后恢复室(PACU)停留时间、PACU期间记录躁动发生情况,采用小儿苏醒期烦躁量表(PAED)评价躁动程度。结果两组手术时间、拔管时间差异无统计学意义(P>0.05)；与Ⅰ组相比,Ⅱ组患者麻醉后PACU停留时间短,躁动发生率低,躁动评分低,差异具有统计学意义(P<0.05)。结论右美托咪定可减少七氟醚复合麻醉斜视矫正术患儿苏醒期躁动发生率,苏醒质量高。
目的：觀察右美託咪定對七氟醚複閤痳醉斜視矯正術患兒囌醒期躁動的影響。方法40例擇期擬行斜視矯正術的患兒,採用隨機數字錶法分成兩組：生理鹽水對照組(Ⅰ組, n=20)和右美託咪定組(Ⅱ組, n=20)。靜脈註射芬太尼2μg/kg,異丙酚3 mg/kg完成誘導插入喉罩,術中吸入2%~3.5%七氟醚維持痳醉。插入喉罩即刻Ⅱ組輸註右美託咪定0.2μg/(kg·h),Ⅰ組輸註等劑量的生理鹽水。手術結束時停止輸註右美託咪定和生理鹽水。記錄兩組手術時間、拔管時間、痳醉後恢複室(PACU)停留時間、PACU期間記錄躁動髮生情況,採用小兒囌醒期煩躁量錶(PAED)評價躁動程度。結果兩組手術時間、拔管時間差異無統計學意義(P>0.05)；與Ⅰ組相比,Ⅱ組患者痳醉後PACU停留時間短,躁動髮生率低,躁動評分低,差異具有統計學意義(P<0.05)。結論右美託咪定可減少七氟醚複閤痳醉斜視矯正術患兒囌醒期躁動髮生率,囌醒質量高。
목적：관찰우미탁미정대칠불미복합마취사시교정술환인소성기조동적영향。방법40례택기의행사시교정술적환인,채용수궤수자표법분성량조：생리염수대조조(Ⅰ조, n=20)화우미탁미정조(Ⅱ조, n=20)。정맥주사분태니2μg/kg,이병분3 mg/kg완성유도삽입후조,술중흡입2%~3.5%칠불미유지마취。삽입후조즉각Ⅱ조수주우미탁미정0.2μg/(kg·h),Ⅰ조수주등제량적생리염수。수술결속시정지수주우미탁미정화생리염수。기록량조수술시간、발관시간、마취후회복실(PACU)정류시간、PACU기간기록조동발생정황,채용소인소성기번조량표(PAED)평개조동정도。결과량조수술시간、발관시간차이무통계학의의(P>0.05)；여Ⅰ조상비,Ⅱ조환자마취후PACU정류시간단,조동발생솔저,조동평분저,차이구유통계학의의(P<0.05)。결론우미탁미정가감소칠불미복합마취사시교정술환인소성기조동발생솔,소성질량고。
Objective To observe the influence of dexmedetomidine on emergence agitation of children undergoing strabismus surgery by sevoflurane anesthesia. Methods A total of 40 children undergoing strabismus surgery were divided into two groups by random number table as normal saline control group (groupⅠ, n=20) and dexmedetomidine group (groupⅡ, n=20). Anesthesia was induced with 2μg/kg of fentanyl and3 mg/kg of propofol, and maintained with 2%~3.5%of sevoflurane. At the moment laryngeal mask intubation was performed, groupⅡreceived 0.2μg/(kg·h) of dexmedetomidine, and groupⅠreceived normal saline. The operation time, extubation time, postanesthesia care unit (PACU) stays time, and agitation during PACU were recorded, and pediatric anesthesia emergence delirium (PAED) was used to assess their agitation degree. Results There were no statistically significant differences of the operation time and extubation time between the two groups (P>0.05). The PACU stays time was shorter, incidence of agitation and PEAD scores were lower in GroupⅡthan in GroupⅠ, and the difference had statistical significance (P<0.05). Conclusion Dexmedetomidine can reduce the incidence of agitation of children who undergo strabismus surgery by sevoflurane anesthesia, and they can also gain high wake quality.
