中华健康管理学杂志
中華健康管理學雜誌
중화건강관이학잡지
CHINESE JOURNAL OF HEALTH MANAGEMENT
2014年
6期
399-402
,共4页
温小恒%徐腾达%盖小荣%孙杰%莎仁高娃
溫小恆%徐騰達%蓋小榮%孫傑%莎仁高娃
온소항%서등체%개소영%손걸%사인고왜
颈动脉%超声检查%动脉粥样硬化%血糖
頸動脈%超聲檢查%動脈粥樣硬化%血糖
경동맥%초성검사%동맥죽양경화%혈당
Carotid arteries%Ultrasonography%Atherosclerosis%Blood glucose
目的 分析中青年体检人群颈动脉粥样硬化检出率及其相关危险因素.方法 2013年4至10月北京协和医院19～59岁的体检者,除外既往有高血压、糖尿病、冠心病、脑血管病、结缔组织疾病者,均接受血压、血糖、血脂和超声颈动脉超声等检查,共入选762名,其中男589名,女173名,平均年龄(46±9)岁.采用t检验计算不同年龄组内(＜40岁、40～49岁、50～59岁),粥样硬化组和无粥样硬化组间血压、血糖、血脂的差别.对年龄、性别、血压、血糖、血脂等危险因素进行logistic回归分析,将年龄进行受试者工作特征曲线(ROC曲线)分析.结果 男性组颈动脉粥样硬化阳性率30.2％(178/589),女性组颈动脉粥样硬化阳性率15.6％(27/173),两组比较差异有统计学意义(x2=14.522,P=0.000).在40～49岁人群,有无颈动脉粥样硬化组间的舒张压[(74.19±8.96) vs.(71.10±9.71)]差异有统计学意义(t=-2.789,P＜0.05);有颈动脉粥样硬化组与无粥样硬化组间在＜40岁[(5.77±1.59)vs.(5.08±0.94)]、40～49岁[(5.43±0.84)vs.(5.19±0.65)]、50～59岁[(5.32±0.70) vs.(5.14±9.46)]各组的血糖差异均有统计学意义(t值分别为-2.256,-2.930,-2.174,P＜0.05).logistic回归分析显示,年龄、性别、舒张压、血糖等4项是中青年健康体检者颈动脉硬化的独立危险因素,回归系数分别为0.993,0.711,0.047,0.334.年龄的ROC曲线下面积为0.731,cut-off值为51岁.结论 对于50岁以上的健康中年男性常规进行颈动脉超声有利于早期明确有无动脉硬化,而对于血糖异常、舒张压升高的人群可能需要更积极地进行这方面的检查.
目的 分析中青年體檢人群頸動脈粥樣硬化檢齣率及其相關危險因素.方法 2013年4至10月北京協和醫院19～59歲的體檢者,除外既往有高血壓、糖尿病、冠心病、腦血管病、結締組織疾病者,均接受血壓、血糖、血脂和超聲頸動脈超聲等檢查,共入選762名,其中男589名,女173名,平均年齡(46±9)歲.採用t檢驗計算不同年齡組內(＜40歲、40～49歲、50～59歲),粥樣硬化組和無粥樣硬化組間血壓、血糖、血脂的差彆.對年齡、性彆、血壓、血糖、血脂等危險因素進行logistic迴歸分析,將年齡進行受試者工作特徵麯線(ROC麯線)分析.結果 男性組頸動脈粥樣硬化暘性率30.2％(178/589),女性組頸動脈粥樣硬化暘性率15.6％(27/173),兩組比較差異有統計學意義(x2=14.522,P=0.000).在40～49歲人群,有無頸動脈粥樣硬化組間的舒張壓[(74.19±8.96) vs.(71.10±9.71)]差異有統計學意義(t=-2.789,P＜0.05);有頸動脈粥樣硬化組與無粥樣硬化組間在＜40歲[(5.77±1.59)vs.(5.08±0.94)]、40～49歲[(5.43±0.84)vs.(5.19±0.65)]、50～59歲[(5.32±0.70) vs.(5.14±9.46)]各組的血糖差異均有統計學意義(t值分彆為-2.256,-2.930,-2.174,P＜0.05).logistic迴歸分析顯示,年齡、性彆、舒張壓、血糖等4項是中青年健康體檢者頸動脈硬化的獨立危險因素,迴歸繫數分彆為0.993,0.711,0.047,0.334.年齡的ROC麯線下麵積為0.731,cut-off值為51歲.結論 對于50歲以上的健康中年男性常規進行頸動脈超聲有利于早期明確有無動脈硬化,而對于血糖異常、舒張壓升高的人群可能需要更積極地進行這方麵的檢查.
목적 분석중청년체검인군경동맥죽양경화검출솔급기상관위험인소.방법 2013년4지10월북경협화의원19～59세적체검자,제외기왕유고혈압、당뇨병、관심병、뇌혈관병、결체조직질병자,균접수혈압、혈당、혈지화초성경동맥초성등검사,공입선762명,기중남589명,녀173명,평균년령(46±9)세.채용t검험계산불동년령조내(＜40세、40～49세、50～59세),죽양경화조화무죽양경화조간혈압、혈당、혈지적차별.대년령、성별、혈압、혈당、혈지등위험인소진행logistic회귀분석,장년령진행수시자공작특정곡선(ROC곡선)분석.결과 남성조경동맥죽양경화양성솔30.2％(178/589),녀성조경동맥죽양경화양성솔15.6％(27/173),량조비교차이유통계학의의(x2=14.522,P=0.000).재40～49세인군,유무경동맥죽양경화조간적서장압[(74.19±8.96) vs.(71.10±9.71)]차이유통계학의의(t=-2.789,P＜0.05);유경동맥죽양경화조여무죽양경화조간재＜40세[(5.77±1.59)vs.(5.08±0.94)]、40～49세[(5.43±0.84)vs.(5.19±0.65)]、50～59세[(5.32±0.70) vs.(5.14±9.46)]각조적혈당차이균유통계학의의(t치분별위-2.256,-2.930,-2.174,P＜0.05).logistic회귀분석현시,년령、성별、서장압、혈당등4항시중청년건강체검자경동맥경화적독립위험인소,회귀계수분별위0.993,0.711,0.047,0.334.년령적ROC곡선하면적위0.731,cut-off치위51세.결론 대우50세이상적건강중년남성상규진행경동맥초성유리우조기명학유무동맥경화,이대우혈당이상、서장압승고적인군가능수요경적겁지진행저방면적검사.
Objective To investigate the relationship between carotid artery atherosclerosis and risk factor in a young and middle-aged population in China who received health checkup.Methods A total of 762 cases of young and middle-aged adult were recruited between April and October in 2013.These subjects had no hypertension,diabetes,coronary heart disease,cerebrovascular disease,and connective tissue disease,etc.Their Blood pressure,serum glucose (Glu),total cholesterol (TC),triglyceride (TG),and low density lipoprotein cholesterol (LDL-C) were measured and carotid artery ultrasonography was performed.Of the 762 cases,589 were male,173 were female,mean age was (46 ± 9) years.For blood pressure,blood lipids,the t test was performed to detect the difference between arteriosclerosis group and non arteriosclerosis group in different age groups.Logistic regression was performed to reveal the risk factors with carotid arteriosclerosis.Results Of the 762 subjects,205 had carotid artery atherosclerosis; 30.2％ (178/589) of them were men and 15.6％(27/173) of them were women,with a significant difference between two groups,(x2=14.522,P=0.000).In the younger than 40 years old group,the diastolic blood pressure has statistical significance between carotid arteriosclerosis and non carotid arteriosclerosis group (t=-2.789,P＜ 0.05); blood sugar had statistically significant difference between the two groups (t value was-2.256,-2.930,-2.174,respectivly,P＜0.05).Multiple regression analysis revealed that the independent risk factors for carotid artery arteriosclerosis were age,sex,DBP,and Glu.The regression coefficients were 0.993,0.711,0.047,0.334 seperately.The ROC curve of age was analyzed,the area under the ROC curve was 0.731,cut-off was 51 years old.Conclusions Routine carotid artery ultrasound should be performed for older than 50 healthy middle-aged men,to determine whether arteriosclerosis exists,especially for people with abnormal blood glucose or elevated DBP.
