CAJ | 학술논문

目的：了解糖尿病足患者截肢率及截肢影响因素。方法：收集2007年1月至2012年3月住院的糖尿病足患者，比较截肢与非截肢组的临床特征，采用Logistic回归分析截肢的主要影响因素。结果：570例糖尿病足患者中有88例（15.4％）接受截肢手术，截肢组足病病程、血白细胞及中性粒细胞比例、饮酒率、多发溃疡率、创面混合感染率高于非截肢组（ P＜0.05）。白蛋白、血红蛋白、HDL－C低于非截肢组（ P＜0.05）。大截肢组创面革兰氏阴性菌比例、多发溃疡率、血白细胞及中性粒细胞比例高于小截肢组，血白蛋白低于小截肢组（ P＜0.05）。Logistic回归分析发现足背动脉、饮酒、贫血、血白细胞是截肢的危险因素，HDL －C是截肢的保护因素。结论：足背动脉搏动差、饮酒、贫血、感染、低HDL－C是糖尿病足患者截肢的主要影响因素。
목적：료해당뇨병족환자절지솔급절지영향인소。방법：수집2007년1월지2012년3월주원적당뇨병족환자，비교절지여비절지조적림상특정，채용Logistic회귀분석절지적주요영향인소。결과：570례당뇨병족환자중유88례（15.4％）접수절지수술，절지조족병병정、혈백세포급중성립세포비례、음주솔、다발궤양솔、창면혼합감염솔고우비절지조（ P＜0.05）。백단백、혈홍단백、HDL－C저우비절지조（ P＜0.05）。대절지조창면혁란씨음성균비례、다발궤양솔、혈백세포급중성립세포비례고우소절지조，혈백단백저우소절지조（ P＜0.05）。Logistic회귀분석발현족배동맥、음주、빈혈、혈백세포시절지적위험인소，HDL －C시절지적보호인소。결론：족배동맥박동차、음주、빈혈、감염、저HDL－C시당뇨병족환자절지적주요영향인소。
Objective ] To evaluate the incidence of amputation among patients with diabetic foot ulcer and risk factors for am-putations .[Method] Inpatients with diabetic foot ulcer were recruited from January 2007 to March 2012 .Clinical character was compared between amputation group and non-amputation group and the critical factors contributing to amputations were ana-lyzed with logistic regression .[Result] 88 patient (15.4% ) underwent amputation .Higher foot ulcer duration, white blood cell counts, neutrophils percentage, rates of alcohol consumption, multiple ulcer and mixed infections and lower plasma albu-min, blood hemoglobin, high-density lipoprotein-cholesterol were found in amputation group compared with the non-ampu-tation group ( P<0.05 ) .The major amputation group had higher white blood cell counts, neutrophils percentage, proportion of Gram-negtive bacteria, rate of multiple ulcer and lower plasma albumin than minor amputation group ( P<0.05 ) .Upon lo-gistic regression analysis, dorsal artery of foot, alcohol consumption, anaemia, white blood cell counts were independent risk factor of amputation, HDL-C was independent protective factor of amputation .[Conclusion] The critical influencing factor for amputation were weakness or absent pulsation of dorsal artery of foot, alcohol consumption, anaemia, infection, low HDL-C.