CAJ | 학술논문

目的：分析肾脏良恶性肿瘤超声造影（CEUS）时间－强度曲线（TIC）特点，探讨相对超声造影参数在鉴别肾脏良恶性肿瘤中的临床应用价值。方法对大连医科大学附属第一医院的67例经病理证实的肾脏肿瘤行CEUS检查，获取TIC曲线和多个定量参数，包括峰值强度（ Peak）、达峰时间（ Tp）、曲线下面积（ AUC）及造影剂平均通过时间（ MTT），比较相对造影参数在肾脏良恶性肿瘤之间的差异。结果恶性肿瘤的相对Peak和相对AUC均明显高于良性肿瘤；恶性肿瘤的相对MTT短于良性肿瘤，差异有显著性意义（P＜0．05）。相对Tp在良恶性肿瘤之间比较差异无显著性意义（P＞0．05）。结论超声造影定量参数分析能够提供更多的血流灌注特征，可为肾脏良恶性肿瘤的诊断及鉴别诊断提供重要的参考依据。
목적：분석신장량악성종류초성조영（CEUS）시간－강도곡선（TIC）특점，탐토상대초성조영삼수재감별신장량악성종류중적림상응용개치。방법대대련의과대학부속제일의원적67례경병리증실적신장종류행CEUS검사，획취TIC곡선화다개정량삼수，포괄봉치강도（ Peak）、체봉시간（ Tp）、곡선하면적（ AUC）급조영제평균통과시간（ MTT），비교상대조영삼수재신장량악성종류지간적차이。결과악성종류적상대Peak화상대AUC균명현고우량성종류；악성종류적상대MTT단우량성종류，차이유현저성의의（P＜0．05）。상대Tp재량악성종류지간비교차이무현저성의의（P＞0．05）。결론초성조영정량삼수분석능구제공경다적혈류관주특정，가위신장량악성종류적진단급감별진단제공중요적삼고의거。
Objective To evaluate the application value of relative contrast-enhanced ultrasound ( CEUS) parameters in differential diagnosis of renal tumors by analyzing quantitatively the characteristics of time-intensity curve ( TIC) .Meth-ods Sixty-seven patients with renal tumors confirmed by surgery and pathology underwent contrast-enhanced ultrasound preoperatively.The time -intensity curves and quantitative parameters were obtained, including peak intensity ( Peak) , time to peak ( Tp) , area under curve ( AUC) and mean transit time ( MTT) .The relative CEUS parameters were compared in benign and malignant renal tumors.Results In malignant tumors, the relative peak intensity and relative area under the curve were more than those of the benign, while the relative mean transit time was less than that of the benign ( P<0.05) . There was no significant difference in relative time to peak between malignant and benign renal tumors.Conclusion CEUS can provide more blood flow perfusion characteristics and provide a reference basis for the diagnosis and differential diagno-sis of benign and malignant renal tumors, which has important clinical application value.