CAJ | 학술논문

目的：分析平顶山市抗菌药不良反应发生的情况，为平顶山市合理应用抗菌药提供参考。方法：收集平顶山市6家大医院2009年5月～2010年5月间的门诊处方13783张，对其中抗菌药的使用不良反应报表分析。结果：9763例抗菌药不良反应中，头孢菌素类药品报告数为30．9％，其次为青霉素类为21．6％，再次为氟喹诺酮类药物为18．9％；不良反应的表现主要以皮肤软组织损害及器官损害较常见。结论：在临床应用抗菌药的过程中既要注意药品的适应证，也要重视药品的不良反应的发生。
목적：분석평정산시항균약불량반응발생적정황，위평정산시합리응용항균약제공삼고。방법：수집평정산시6가대의원2009년5월～2010년5월간적문진처방13783장，대기중항균약적사용불량반응보표분석。결과：9763례항균약불량반응중，두포균소류약품보고수위30．9％，기차위청매소류위21．6％，재차위불규낙동류약물위18．9％；불량반응적표현주요이피부연조직손해급기관손해교상견。결론：재림상응용항균약적과정중기요주의약품적괄응증，야요중시약품적불량반응적발생。
Objective:To investigate the characteristics and regularities of adverse drug reactions ( ADR) induced by antibac-teria1 drugs.The results would provide the reference for rational use of antibacterial drugs in Pingdingshan city .Methods:Anal-ysis on 13783 outpatient prescriptions showed the reports of ADR cases induced by antibacterial drugs occurred in six hospitals of Pingdingshan from May 2009 to May 2010 .Results:9763 ADR cases were chiefly induced by cephalosporins 30 .9%, followed by penicillins 21.6%, fluoroquinolones was the third 18.9%.The main types of drugs adverse reaction were skin soft tissue damages, fol1 owed by organ damages.Conclusion:Our research worth the highest alert in the clinic to reduce the incidence of ADR induced by antibacterial drugs.In the process of the clinical application of antibacterial drugs, doctors should pay attention to the indications and adverse reactions.