北华大学学报（自然科学版）
北華大學學報（自然科學版）
북화대학학보（자연과학판）
JOURNAL OF BEIHUA UNIVERSITY(NATURAL SCIENCE)
2014年
6期
772-774
,共3页
泌尿生殖道感染%支原体%药敏试验%耐药性
泌尿生殖道感染%支原體%藥敏試驗%耐藥性
비뇨생식도감염%지원체%약민시험%내약성
genitourinary tract infection%mycoplasma%drug sensitivity%resistance
目的：通过对支原体的检测及药敏情况来分析患者耐药程度，指导临床合理用药.方法用支原体( Uu/Mh)分离培养药敏试剂盒对不同患者进行药物敏感性试验，并对其结果进行统计分析.结果250例患者的泌尿生殖道分泌物中分离支原体感染92例，标本阳性率为36.8%，其中解脲支原体(Uu)75例，阳性率为81.5%；人型支原体(Mh)3例，阳性率为3.2%；混合感染(Uu+Mh)14例，阳性率为15.3%；药敏结果显示：支原体对12种抗生素中交沙霉素、多西环素、美满霉素和四环素的平均敏感率较高，分别为(93.02±7.15)%、(90.19±10.83)%、(86.03±14.30)%、(82.76±17.89)%，而对环丙沙星、左氧氟沙星、氧氟沙星和司巴沙星的敏感性较低；耐药性最强的抗生素是环丙沙星和左氧氟沙星.结论交沙霉素、多西环素、美满霉素和四环素可作为泌尿生殖道支原体感染的临床经验性选用的抗菌药物；支原体的培养及药敏试验可以掌握支原体的流行状况及耐药程度，为临床合理用药提供参考.
目的：通過對支原體的檢測及藥敏情況來分析患者耐藥程度，指導臨床閤理用藥.方法用支原體( Uu/Mh)分離培養藥敏試劑盒對不同患者進行藥物敏感性試驗，併對其結果進行統計分析.結果250例患者的泌尿生殖道分泌物中分離支原體感染92例，標本暘性率為36.8%，其中解脲支原體(Uu)75例，暘性率為81.5%；人型支原體(Mh)3例，暘性率為3.2%；混閤感染(Uu+Mh)14例，暘性率為15.3%；藥敏結果顯示：支原體對12種抗生素中交沙黴素、多西環素、美滿黴素和四環素的平均敏感率較高，分彆為(93.02±7.15)%、(90.19±10.83)%、(86.03±14.30)%、(82.76±17.89)%，而對環丙沙星、左氧氟沙星、氧氟沙星和司巴沙星的敏感性較低；耐藥性最彊的抗生素是環丙沙星和左氧氟沙星.結論交沙黴素、多西環素、美滿黴素和四環素可作為泌尿生殖道支原體感染的臨床經驗性選用的抗菌藥物；支原體的培養及藥敏試驗可以掌握支原體的流行狀況及耐藥程度，為臨床閤理用藥提供參攷.
목적：통과대지원체적검측급약민정황래분석환자내약정도，지도림상합리용약.방법용지원체( Uu/Mh)분리배양약민시제합대불동환자진행약물민감성시험，병대기결과진행통계분석.결과250례환자적비뇨생식도분비물중분리지원체감염92례，표본양성솔위36.8%，기중해뇨지원체(Uu)75례，양성솔위81.5%；인형지원체(Mh)3례，양성솔위3.2%；혼합감염(Uu+Mh)14례，양성솔위15.3%；약민결과현시：지원체대12충항생소중교사매소、다서배소、미만매소화사배소적평균민감솔교고，분별위(93.02±7.15)%、(90.19±10.83)%、(86.03±14.30)%、(82.76±17.89)%，이대배병사성、좌양불사성、양불사성화사파사성적민감성교저；내약성최강적항생소시배병사성화좌양불사성.결론교사매소、다서배소、미만매소화사배소가작위비뇨생식도지원체감염적림상경험성선용적항균약물；지원체적배양급약민시험가이장악지원체적류행상황급내약정도，위림상합리용약제공삼고.
Objective The degree of resistance was analyzed by investigating the detection and drug sensitivity of mycoplasma to guide the rational drug application in clinic. Method A mycoplasma(Uu/Mh)separation and culture drug sensitivity kit was used to test the drug sensitivity in different patients, and the results were statistically analyzed. Results 92 cases among of 250 patients with urogenital tract secretions were found with mycoplasma infection and the positive mycoplasma rate was 36. 8%,of which there were 75 cases with Ureaplasma urealyticum(Uu)infection and the positive rate was 81. 5%,3 cases with Mycoplasma hominis(Mh)infection and the positive rate was 3. 2%,and 14 cases with mixed infection(Uu+Mh)infection and the positive rate was 15. 3%. The drug susceptibility results showed that the average sensitivity rate of mycoplasma pneumoniae to josamycin, doxycycline,minocycline and tetracycline was higher,93. 02±7. 15%,90. 19±10. 83%,86. 03±14. 30% and 82. 76±17. 89% respectively. However,the sensitivity to ciprofloxacin,levofloxacin,ofloxacin and sparfloxacin was lower. The antibiotics with the strongest resistance were ciprofloxacin and levofloxacin. Conclusion Josamycin,doxycycline, minocycline and tetracycline can be used as antibacterial drugs for the clinical mycoplasma infection of urogenital tract selection. Mycoplasma culture and drug sensitivity test can understand the epidemic situation and drug resistance of it and provide the reference for the clinical use.
