CAJ | 학술논문

目的：探讨脐血25(OH)D水平及其与孕母外周血25(OH)D水平的相关性。方法于2010年11月至2011年1月，采用酶联免疫法测定100例新生儿脐血及其中20例选择性剖宫产的孕母生产前1 d静脉血25(OH)D水平，并进行相关性分析。结果100例新生儿脐血25(OH)D平均水平为(29.77±12.51)nmol/L，90例(90%)<50 nmol/L属于缺乏；20例孕母静脉血25(OH)D平均水平为(23.42±5.23)nmol/L，与对应的新生儿脐血25(OH)D水平呈显著正相关(r=0.84，P<0.001)。结论新生儿脐血维生素D水平偏低，与孕母血25(OH)D水平相关。
목적：탐토제혈25(OH)D수평급기여잉모외주혈25(OH)D수평적상관성。방법우2010년11월지2011년1월，채용매련면역법측정100례신생인제혈급기중20례선택성부궁산적잉모생산전1 d정맥혈25(OH)D수평，병진행상관성분석。결과100례신생인제혈25(OH)D평균수평위(29.77±12.51)nmol/L，90례(90%)<50 nmol/L속우결핍；20례잉모정맥혈25(OH)D평균수평위(23.42±5.23)nmol/L，여대응적신생인제혈25(OH)D수평정현저정상관(r=0.84，P<0.001)。결론신생인제혈유생소D수평편저，여잉모혈25(OH)D수평상관。
Object To explore the relationship of 25 (OH) D levels in cord and maternal peripheral blood to understand the maternal and neonatal vitamin D status in Songjiang District of Shanghai. Methods One hundred newborns delivered at the First People’s Hospital afifliated to Shanghai Jiaotong University and 20 pregnant women during November 2010 to January 2011 in Songjiang district were enrolled in the study. The levels of 25 (OH) D in cord and maternal blood were measured by ELISA and compared. Results Mean materna1 serum levels of 25 (OH) D was (23.42±5.23) nmol/L, and cord blood 25 (OH) D was (29.77±12.51) nmol/L. Maternal serum 25 (OH) D was positively correlated with cord blood 25 (OH) D (r=0.84, P<0.001). Conclusions This study shows that the prevalence of vitamin D deifciency in pregnant women is high in Shanghai Songjiang District, which could have adverse effects on newbowns.