CAJ | 학술논문

为了研究血管对消融温度场的影响，运用离体实验的方法测定距天线不同距离及血流量不同的血管对温度场的影响.实验中采用输液管代替肝动脉，并依据肝动脉的血流速度设定管内的水流速度；利用铜-康铜热电偶测量血管周围的温度场.并在相同的条件下进行微波消融的仿真计算，对比实验与仿真结果的不同.结果显示：当微波天线距血管1.0 cm 时，由于血液对流换热的影响，微波消融域并没有关于微波天线对称，在靠近血管的一侧出现了很大的温度梯度，且随着血流量的增大，微波消融域变小；当微波天线距离血管1.5 cm 时，微波消融域的形状开始变圆，并且天线两侧相同距离的点的温升曲线的温差也开始减小；当微波天线距离血管2.0 cm 时，微波消融域几乎呈圆形，且关于微波天线对称，血管的影响可以忽略.当血流量增大时(从22 cm/ s 变为55 cm/ s)，血管对温度场的影响增大(与22 cm/ s 的温差最大可达10℃)，消融温度场进一步减小.当微波天线与血管之间的距离大于2.0 cm 时，对于小流量的血管可以忽略其对于温度场的影响，热疗前不用进行血管阻断术.当微波天线与血管之间的距离小于2.0 cm 且血流量大于22 cm/ s 时，为了不影响消融的疗效，建议进行血管阻断术.
위료연구혈관대소융온도장적영향，운용리체실험적방법측정거천선불동거리급혈류량불동적혈관대온도장적영향.실험중채용수액관대체간동맥，병의거간동맥적혈류속도설정관내적수류속도；이용동-강동열전우측량혈관주위적온도장.병재상동적조건하진행미파소융적방진계산，대비실험여방진결과적불동.결과현시：당미파천선거혈관1.0 cm 시，유우혈액대류환열적영향，미파소융역병몰유관우미파천선대칭，재고근혈관적일측출현료흔대적온도제도，차수착혈류량적증대，미파소융역변소；당미파천선거리혈관1.5 cm 시，미파소융역적형상개시변원，병차천선량측상동거리적점적온승곡선적온차야개시감소；당미파천선거리혈관2.0 cm 시，미파소융역궤호정원형，차관우미파천선대칭，혈관적영향가이홀략.당혈류량증대시(종22 cm/ s 변위55 cm/ s)，혈관대온도장적영향증대(여22 cm/ s 적온차최대가체10℃)，소융온도장진일보감소.당미파천선여혈관지간적거리대우2.0 cm 시，대우소류량적혈관가이홀략기대우온도장적영향，열료전불용진행혈관조단술.당미파천선여혈관지간적거리소우2.0 cm 차혈류량대우22 cm/ s 시，위료불영향소융적료효，건의진행혈관조단술.
To study the effect of the vessel on the ablation field, the temperature field near the blood vessel at different distances from the antenna and different blood flow rates were measured in vitro experiments. Using infusion tube instead of hepatic lartery, and setting the flow rate based on the blood flow velocity of the hepatic artery, copper-constantan thermocouples ( TCs) were used to measure the temperature near the blood vessel in vitro experiments, which were compared with the simulation results in the same condition. Experimental results showed that when the microwave antenna was 1. 0 cm away from the vessel, the heating pattern was not symmetrical about the antenna because the heat convective of blood, and large temperature gradient existed in the side of the blood vessel. The greater the blood flow was, the smaller the temperature field of microwave ablation was. When the antenna was 1. 5 cm away from the blood vessel, the heating pattern was more circular, and the temperature contours of two blood flows were almost overlapped. When the antenna was 2. 0 cm away from the blood vessel, the heating pattern was circle, and almost symmetrical about the microwave antenna. When the blood flow increased ( from 22 cm/ s to 55 cm/ s), vessel influence on the temperature field increased ( the temperature difference with 22 cm/ s up to 10 ℃), and temperature fields further reduced. The effect of blood on the temperature field could be ignored if the distance between blood vessel and the microwave antenna exceeded 2. 0 cm. When the distance was less than 2. 0 cm and the blood velocity was more than 22 cm/s, in order not to affect the efficacy of the ablation, blood vessel blocking was suggested to implement.