中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
21期
54-54,55
,共2页
氯霉素氧化锌乳膏%制备%质量标准
氯黴素氧化鋅乳膏%製備%質量標準
록매소양화자유고%제비%질량표준
Chloramphenicol and Zinc Oxide Cream%preparation%quality standard
目的：制备氯霉素氧化锌乳膏并建立质量标准。方法以羊毛脂等为辅料、氯霉素为主药制备氯霉素氧化锌乳膏。采用高效液相色谱法测定制剂中氯霉素的含量。结果所制备氯霉素氧化锌乳膏质量稳定，氯霉素的质量浓度线性范围为100~400μg/mL（ r=0.9999），平均回收率为99.67%，RSD为0.78%( n=9)。结论该制剂制备简便、合理可行，质量控制标准准确、可靠。
目的：製備氯黴素氧化鋅乳膏併建立質量標準。方法以羊毛脂等為輔料、氯黴素為主藥製備氯黴素氧化鋅乳膏。採用高效液相色譜法測定製劑中氯黴素的含量。結果所製備氯黴素氧化鋅乳膏質量穩定，氯黴素的質量濃度線性範圍為100~400μg/mL（ r=0.9999），平均迴收率為99.67%，RSD為0.78%( n=9)。結論該製劑製備簡便、閤理可行，質量控製標準準確、可靠。
목적：제비록매소양화자유고병건립질량표준。방법이양모지등위보료、록매소위주약제비록매소양화자유고。채용고효액상색보법측정제제중록매소적함량。결과소제비록매소양화자유고질량은정，록매소적질량농도선성범위위100~400μg/mL（ r=0.9999），평균회수솔위99.67%，RSD위0.78%( n=9)。결론해제제제비간편、합리가행，질량공제표준준학、가고。
Objective To prepare Chloramphenicol and Zinc Oxide Cream and to establish its quality standard. Methods Chlorampheni-col and Zinc Oxide Cream was prepared with lanolin as accessory and chloramphenicol as main drug. The chloramphenicol content in the preparation was determined by HPLC. Results The prepared Chloramphenicol and Zinc Oxide Cream was shown to be stable in quality. The linear range of chloramphenicol was 100-400μg/mL ( r=0. 999 9 ) . The average recovery rate was 99. 67%( n=9 ) , RSD=0. 78%( n=9 ) . Conclusion This preparation is simple in preparation, rational and feasible;its quality standard is accurate and reliable.
