中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
21期
45-46
,共2页
电感耦合等离子体质谱法%明胶空心胶囊%铬元素%含量测定
電感耦閤等離子體質譜法%明膠空心膠囊%鉻元素%含量測定
전감우합등리자체질보법%명효공심효낭%락원소%함량측정
ICP-MS%gelatin hollow capsules%chromium%content determination
目的：建立测定药用明胶空心胶囊中铬元素含量的电感耦合等离子体质谱( ICP－MS )法。方法采用微波消解法进行样品前处理，再经电感耦合等离子质谱法，以锗为内标进行测定。结果铬元素质量浓度线性范围为2~40μg/L，回归方程相关系数 r=0.9999，方法的检出限为0.006μg/L，回收率为92.90%~108.40%。结论该方法快捷、准确、灵敏度高，适用于铬元素含量的测定。
目的：建立測定藥用明膠空心膠囊中鉻元素含量的電感耦閤等離子體質譜( ICP－MS )法。方法採用微波消解法進行樣品前處理，再經電感耦閤等離子質譜法，以鍺為內標進行測定。結果鉻元素質量濃度線性範圍為2~40μg/L，迴歸方程相關繫數 r=0.9999，方法的檢齣限為0.006μg/L，迴收率為92.90%~108.40%。結論該方法快捷、準確、靈敏度高，適用于鉻元素含量的測定。
목적：건립측정약용명효공심효낭중락원소함량적전감우합등리자체질보( ICP－MS )법。방법채용미파소해법진행양품전처리，재경전감우합등리자질보법，이타위내표진행측정。결과락원소질량농도선성범위위2~40μg/L，회귀방정상관계수 r=0.9999，방법적검출한위0.006μg/L，회수솔위92.90%~108.40%。결론해방법쾌첩、준학、령민도고，괄용우락원소함량적측정。
Objective To establish an inductively coupled plasma mass spectrometry ( ICP-MS method for the determination of the chromium content in gelatin hollow capsule. Methods The samples were pre-treated by the microwave digestion method. Chromium was directly detected by ICP-MS with germanium as internal standard element. Results The linear range was 2-40 μg/L ( r=0. 999 9 ) , the detection limit was 0. 006μg/L and the recovery rate was 92. 90% -108. 40%. Conclusion This method is rapid, accurate, highly sensitive and suitable for determining the chromium content in gelatin hollow capsules.
